CdSe/ZnS电化学发光法测定去甲肾上腺素

田利; 赵越; 汪雪融; 吴可欣; 齐艳娟; 李天娇; 陈瑞战

doi:10.3788/fgxb20183907.1024

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CdSe/ZnS电化学发光法测定去甲肾上腺素

发光学应用及交叉前沿 | 更新时间：2020-08-12

- CdSe/ZnS电化学发光法测定去甲肾上腺素
- Electrochemiluminescent Determination of Norepinephrine by CdSe/ZnS Quantum Dot Modified Gold Electrode
- 发光学报 2018年39卷第7期页码：1024-1028
- 作者机构：
  
  长春师范大学化学学院,吉林长春,130032
- 作者简介：
- 基金信息：
  
  吉林省教育"();十三五"();科学技术研究项目()
- DOI：10.3788/fgxb20183907.1024
  中图分类号： O657
- 纸质出版日期：2018-7-5，
  
  网络出版日期：2018-4-2，
  
  收稿日期：2017-11-16，
  
  修回日期：2017-12-21，
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田利, 赵越, 汪雪融等. CdSe/ZnS电化学发光法测定去甲肾上腺素[J]. 发光学报, 2018,39(7): 1024-1028

TIAN Li, ZHAO Yue, WANG Xue-rong etc. Electrochemiluminescent Determination of Norepinephrine by CdSe/ZnS Quantum Dot Modified Gold Electrode[J]. Chinese Journal of Luminescence, 2018,39(7): 1024-1028
田利, 赵越, 汪雪融等. CdSe/ZnS电化学发光法测定去甲肾上腺素[J]. 发光学报, 2018,39(7): 1024-1028 DOI： 10.3788/fgxb20183907.1024.

TIAN Li, ZHAO Yue, WANG Xue-rong etc. Electrochemiluminescent Determination of Norepinephrine by CdSe/ZnS Quantum Dot Modified Gold Electrode[J]. Chinese Journal of Luminescence, 2018,39(7): 1024-1028 DOI： 10.3788/fgxb20183907.1024.

摘要

以巯基丙酸为稳定剂制备了水溶性CdSe/ZnS量子点，并采用滴涂法制备了CdSe/ZnS修饰的金电极（CdSe/ZnS/GE），研究其电化学发光（ECL）性质，考察了pH、CdSe/ZnS浓度、扫描速度、静置时间等实验条件对ECL强度的影响。结果表明，在碱性溶液中，去甲肾上腺素（NE）在鲁米诺溶液中对CdSe/ZnS的电化学发光信号有明显的增敏作用，由此建立了一种检测去甲肾上腺素的新方法。当去甲肾上腺素的浓度（

）在2.310

-5

~1.010

-8

mol/L范围内时，去甲肾上腺素的浓度与相对电化学发光强度呈现良好的线性关系。线性回归方程为I

ECL

=118.788

-15.333（

=0.994 4），最低检测限（

=3）为0.3310

-8

mol/L。

Abstract

Mercaptopropionic acid capped CdSe/ZnS quantum dots(QDs) were synthesized in aqueous solution. The CdSe/ZnS QDs modified gold electrode was prepared. The electrochemical luminescence of this modified electrode was studied. Several experiment factors

such as pH of buffer solution

the concentration of CdSe/ZnS QDs

scan rate and rest time were selected. The results show that the CdSe/ZnS modified electrode has an obvious ECL signal of luminol systems in alkaline media

and norepinephrine can enhance electrochemical luminescence(ECL) signal of the luminol system. Based on these

a novel electrochemical luminescence method for the determination of norepinephrine was developed. Under the optimum conditions

ECL intensities had good linearity with the concentration of norepinephrine and the linear range was widely extended from 2.310

-5

-1.010

-8

mol/L. The linear regression equation is I

ECL

=118.788

-15.333

and the correlation coefficient was 0.994 4. The detection limit is 0.3310

-8

mol/L.

关键词

巯基丙酸CdSe/ZnS量子点电化学发光去甲肾上腺素

Keywords

mercaptopropionic acidCdSe/ZnS quantum dotelectrochemical Luminescence(ECL)norepinephrine(NE)

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