Preparation of Water-soluble Sm∶ZnO-NH<sub>2</sub> QDs Fluorescent Probe and Its Application for Selective Detection of Dopamine

CUI Meijia; HUANG Qiumei; HUANG Wenyi; CUI Bao; RONG Xilin; ZHANG Guoqiang; CHENG Hao; FENG Jun

doi:10.37188/CJL.20220296

您当前的位置：

首页 >

文章列表页 >

Preparation of Water-soluble Sm∶ZnO-NH₂ QDs Fluorescent Probe and Its Application for Selective Detection of Dopamine

Luminescence Applications and Interdisciplinary Fields | 更新时间：2023-03-13

- Preparation of Water-soluble Sm∶ZnO-NH₂ QDs Fluorescent Probe and Its Application for Selective Detection of Dopamine
  增强出版
- Chinese Journal of Luminescence Vol. 44, Issue 2, Pages: 374-386(2023)
- 作者机构：
  
  1.广西科技大学生物与化学工程学院，广西糖资源绿色加工重点实验室，广西柳州　545006
  2.蔗糖产业省部共建协同创新中心，广西南宁　530004
- 作者简介：
- 基金信息：
  
  Fund Project ： Guangxi Key Laboratory of Green Processing of Sugar Resources Open Project(GXTZY202006);Funded Project, Guangxi Graduate Education Innovation Program Project(YCSW2022447)
- DOI：10.37188/CJL.20220296
  CLC： O482.31
- Published：05 February 2023，
  
  Received：22 August 2022，
  
  Revised：12 September 2022，
扫描看全文
崔美佳,黄秋梅,黄文艺等.水溶性Sm∶ZnO⁃NH₂量子点荧光探针制备及其用于选择性检测多巴胺[J].发光学报,2023,44(02):374-386.

CUI Meijia,HUANG Qiumei,HUANG Wenyi,et al.Preparation of Water-soluble Sm∶ZnO-NH₂ QDs Fluorescent Probe and Its Application for Selective Detection of Dopamine[J].Chinese Journal of Luminescence,2023,44(02):374-386.
崔美佳,黄秋梅,黄文艺等.水溶性Sm∶ZnO⁃NH₂量子点荧光探针制备及其用于选择性检测多巴胺[J].发光学报,2023,44(02):374-386. DOI： 10.37188/CJL.20220296.

CUI Meijia,HUANG Qiumei,HUANG Wenyi,et al.Preparation of Water-soluble Sm∶ZnO-NH₂ QDs Fluorescent Probe and Its Application for Selective Detection of Dopamine[J].Chinese Journal of Luminescence,2023,44(02):374-386. DOI： 10.37188/CJL.20220296.

摘要

采用3⁃氨丙基三乙氧基硅烷（APTEs）封端氧化锌量子点（ZnO QDs）的方式，制备了一种荧光性能稳定的水溶性Sm∶ZnO⁃NH

QDs荧光探针。通过透射电子显微镜（TEM）、X射线衍射（XRD）、X射线光电子能谱（XPS）、傅里叶变换红外光谱仪（FT⁃IR）、纳米粒度和Zeta电位仪（DLS）、稳瞬态荧光光谱仪（PL）等对材料进行表征。最优化条件下制备的该探针在水中具有良好的荧光性能，在4 ℃下贮存10 d后其荧光强度仍保留92%。基于该探针的荧光可以直接被多巴胺（DA）选择性猝灭，建立了一种选择性检测DA含量的荧光分析新方法，在50~1 600 ng/mL浓度内，该探针呈现良好的线性关系（

=0.4639

+ 0.008530，

=0.996 3），检出限（LOD）为1.08 ng/mL，具有较好的稳定性和重现性，并成功应用于人体尿液样品的检测，回收率为98.18%~107.84%。

Abstract

In this paper， a water-soluble Sm∶ZnO-NH

QDs fluorescent probe with stable fluorescence performance was prepared by means of 3-aminopropyltriethoxysilane（APTEs） terminated zinc oxide quantum dots（ZnO QDs）. Materials were characterized by transmission electron microscopy（TEM）， X-ray diffraction（XRD）， X-ray photoelectron spectroscopy（XPS）， Fourier transform infrared spectrometer（FT-IR）， nanoparticles size and Zeta potentiometers（DLS）， steady transient fluorescence spectrometer（PL），

etc

. The probe prepared under optimal conditions has good fluorescence performance in water， and its fluorescence intensity remains 92% after 10 d of storage at 4 ℃. Based on the probe fluorescence can be directly quenched by dopamine（DA）， a new method for fluorescence analysis for selective detection of DA content was established， and the probe showed a good linear relationship（

=0.46393

+0.008530，

=0.996 3） and a detection limit of 1.08 ng/mL within a concentration of 50-1 600 ng/mL， which had good stability and reproducibility. It was successfully applied to the detection of human urine samples， and the recovery rate was 98.18% to 107.84%.

关键词

Sm掺杂ZnO-NH2 QDs荧光探针选择性猝灭多巴胺

Keywords

Sm dopedZnO-NH2 QDsfluorescence probeselective quenchingdopamine

references

ENSAFI A A， ZAKERY M， REZAEI B. An optical sensor with specific binding sites for the detection of thioridazine hydrochloride based on ZnO-QDs coated with molecularly imprinted polymer ［J］. Spectrochim. Acta Part A： Mol. Biomol. Spectrosc.， 2019， 206： 460-465. doi: 10.1016/j.saa.2018.08.040http://dx.doi.org/10.1016/j.saa.2018.08.040

ROSHINI A， JAGADEESAN S， ARIVAZHAGAN L， et al. pH-sensitive tangeretin-ZnO quantum dots exert apoptotic and anti-metastatic effects in metastatic lung cancer cell line ［J］. Mat. Sci. Eng.： C， 2018， 92： 477-488. doi: 10.1016/j.msec.2018.06.073http://dx.doi.org/10.1016/j.msec.2018.06.073

YE Y F. Photoluminescence property adjustment of ZnO quantum dots synthesized via sol‑gel method ［J］. J. Mater. Sci.： Mater. Electron.， 2018， 29（6）： 4967-4974. doi: 10.1007/s10854-017-8457-2http://dx.doi.org/10.1007/s10854-017-8457-2

BADILLI U， MOLLARASOULI F， BAKIRHAN N K， et al. Role of quantum dots in pharmaceutical and biomedical analysis， and its application in drug delivery ［J］. TrAC Trends Anal. Chem.， 2020， 131： 116013-1-12. doi: 10.1016/j.trac.2020.116013http://dx.doi.org/10.1016/j.trac.2020.116013

WOLSKA E， KASZEWSKI J， KIEBIK P， et al. Rare earth activated ZnO nanoparticles as biomarkers ［J］. Opt. Mater.， 2014， 36（10）： 1655-1659. doi: 10.1016/j.optmat.2013.12.032http://dx.doi.org/10.1016/j.optmat.2013.12.032

MATSUYAMA K， IHSAN N， IRIE K， et al. Bioimaging application of highly luminescent silica-coated ZnO-nanoparticle quantum dots with biotin ［J］. J. Colloid Interface Sci.， 2013， 399： 19-25. doi: 10.1016/j.jcis.2013.02.047http://dx.doi.org/10.1016/j.jcis.2013.02.047

张佳楠，常开文，李琼，等. 半导体聚合物纳米荧光探针的制备及生物应用研究进展［J］. 发光学报， 2015， 36（7）： 725-737. doi: 10.3788/fgxb20153607.0725http://dx.doi.org/10.3788/fgxb20153607.0725

ZHANG J N， CHANG K W， LI Q， et al. Preparation， regulation and biological application of fluorescent semiconducting polymer dots ［J］. Chin. J. Lumin.， 2015， 36（7）： 725-737. （in Chinese）. doi: 10.3788/fgxb20153607.0725http://dx.doi.org/10.3788/fgxb20153607.0725

LUO C， HOU C Y， ZHANG Q H， et al. A noise-reduced broad-spectrum photodetector based on reagent-free electrophoretic assembled flexible ZnO/rGO films ［J］. Appl. Surf. Sci.， 2019， 469： 113-117. doi: 10.1016/j.apsusc.2018.11.012http://dx.doi.org/10.1016/j.apsusc.2018.11.012

SUN Y J， YANG H Y， ZHAO Z T， et al. Fabrication of ZnO quantum dots@SnO2 hollow nanospheres hybrid hierarchical structures for effectively detecting formaldehyde ［J］. Sens. Actuators B： Chem.， 2020， 318： 128222-1-10. doi: 10.1016/j.snb.2020.128222http://dx.doi.org/10.1016/j.snb.2020.128222

JUNG H， CHO W， YOO R， et al. Highly selective real-time detection of breath acetone by using ZnO quantum dots with a miniaturized gas chromatographic column ［J］. Sens. Actuators B： Chem.， 2018， 274： 527-532. doi: 10.1016/j.snb.2018.07.144http://dx.doi.org/10.1016/j.snb.2018.07.144

LI L， ZHAI T Y， BANDO Y， et al. Recent progress of one-dimensional ZnO nanostructured solar cells ［J］. Nano Energy， 2012， 1（1）： 91-106. doi: 10.1016/j.nanoen.2011.10.005http://dx.doi.org/10.1016/j.nanoen.2011.10.005

VANHEUSDEN K， WARREN W L， SEAGER C H， et al. Mechanisms behind green photoluminescence in ZnO phosphor powders ［J］. J. Appl. Phys.， 1996， 79（10）： 7983-7990. doi: 10.1063/1.362349http://dx.doi.org/10.1063/1.362349

XIONG H M， SHCHUKIN D G， MÖHWALD H， et al. Sonochemical synthesis of highly luminescent zinc oxide nanoparticles doped with magnesium（II）［J］. Angew. Chem. Int. Ed.， 2009， 48（15）： 2727-2731. doi: 10.1002/anie.200805590http://dx.doi.org/10.1002/anie.200805590

HUANG W Y， LV X W， TAN J L， et al. Regulable preparation of the oxygen vacancy of ZnO QDs and their fluorescence performance ［J］. J. Mol. Struct.， 2019， 1195： 653-658. doi: 10.1016/j.molstruc.2019.05.105http://dx.doi.org/10.1016/j.molstruc.2019.05.105

JAGGI N， RATHEE N. Samarium3+-doped CdSe quantum dots for improved electro-optical properties ［J］. Mater. Today： Proc.， 2019， 16： 201-205. doi: 10.1016/j.matpr.2019.05.246http://dx.doi.org/10.1016/j.matpr.2019.05.246

YANG J H， LI X， LANG J H， et al. Effects of mineralizing agent on the morphologies and photoluminescence properties of Eu3+-doped ZnO nanomaterials ［J］. J. Alloys Compd.， 2011， 509（41）： 10025-10031. doi: 10.1016/j.jallcom.2011.08.021http://dx.doi.org/10.1016/j.jallcom.2011.08.021

LU G， YU G H， KONG X， et al. Porphyrin/MoS2 film for ultrasensitive dopamine detection ［J］. Inorg. Chem. Commun.， 2019， 110： 107591-1-5. doi: 10.1016/j.inoche.2019.107591http://dx.doi.org/10.1016/j.inoche.2019.107591

BEREZHNOV A V， FEDOTOVA E I， SERGEEV A I， et al. Dopamine controls neuronal spontaneous calcium oscillations via astrocytic signal ［J］. Cell Calcium， 2021， 94： 102359. doi: 10.1016/j.ceca.2021.102359http://dx.doi.org/10.1016/j.ceca.2021.102359

IMMANUEL S， APARNA T K， SIVASUBRAMANIAN R. A facile preparation of Au-SiO2 nanocomposite for simultaneous electrochemical detection of dopamine and uric acid ［J］. Surf. Interfaces， 2019， 14： 82-91. doi: 10.1016/j.surfin.2018.11.010http://dx.doi.org/10.1016/j.surfin.2018.11.010

WEI X， ZHANG Z D， WANG Z H. A simple dopamine detection method based on fluorescence analysis and dopamine polymerization ［J］. Microchem. J.， 2019， 145： 55-58. doi: 10.1016/j.microc.2018.10.004http://dx.doi.org/10.1016/j.microc.2018.10.004

KADAM V V， BALAKRISHNAN R M， PONNAN ETTIYAPPAN J， et al. Sensing of p-nitrophenol in aqueous solution using zinc oxide quantum dots coated with APTES ［J］. Environ. Nanotechnol.， Monit. Manage.， 2021， 16： 100474. doi: 10.1016/j.enmm.2021.100474http://dx.doi.org/10.1016/j.enmm.2021.100474

ZHOU T， SU Z， TU Y F， et al. Determination of dopamine based on its enhancement of gold-silver nanocluster fluorescence ［J］. Spectrochim. Acta Part A： Mol. Biomol. Spectrosc.， 2021， 252： 119519-1-6. doi: 10.1016/j.saa.2021.119519http://dx.doi.org/10.1016/j.saa.2021.119519

HANNAH S， AL-HATMI M， GRAY L， et al. Low-cost， thin-film， mass-manufacturable carbon electrodes for detection of the neurotransmitter dopamine ［J］. Bioelectrochemistry， 2020， 133： 107480-1-9. doi: 10.1016/j.bioelechem.2020.107480http://dx.doi.org/10.1016/j.bioelechem.2020.107480

XU B B， SU Y Y， LI L， et al. Thiol-functionalized single-layered MoS2 nanosheet as a photoluminescence sensing platform via charge transfer for dopamine detection ［J］. Sens. Actuators B： Chem.， 2017， 246： 380-388. doi: 10.1016/j.snb.2017.02.110http://dx.doi.org/10.1016/j.snb.2017.02.110

ZHAO D， SONG H J， HAO L Y， et al. Luminescent ZnO quantum dots for sensitive and selective detection of dopamine ［J］. Talanta， 2013， 107： 133-139. doi: 10.1016/j.talanta.2013.01.006http://dx.doi.org/10.1016/j.talanta.2013.01.006

HUANG W Y， BAI D W， LI L J， et al. The synthesis of ultrasmall ZnO@PEG nanoparticles and its fluorescence properties ［J］. J. Sol⁃Gel. Sci. Technol.， 2015， 74（3）： 718-725. doi: 10.1007/s10971-015-3653-0http://dx.doi.org/10.1007/s10971-015-3653-0

黄秋梅，吕晓威，谭嘉麟，等. Sm掺杂ZnO QDs的制备及其荧光性能研究［J］. 无机盐工业， 2020， 52（8）： 30-35. doi: 10.11962/1006-4990.2019-0498http://dx.doi.org/10.11962/1006-4990.2019-0498

HUANG Q M， LÜ X W， TAN J L， et al. Preparation of Sm doped ZnO QDs and its fluorescence performance ［J］. Inorg. Chem. Ind.， 2020， 52（8）： 30-35. （in Chinese）. doi: 10.11962/1006-4990.2019-0498http://dx.doi.org/10.11962/1006-4990.2019-0498

CAGLAR Y， CAGLAR M， ILICAN S. XRD， SEM， XPS studies of Sb doped ZnO films and electrical properties of its based Schottky diodes ［J］. Optik， 2018， 164： 424-432. doi: 10.1016/j.ijleo.2018.03.017http://dx.doi.org/10.1016/j.ijleo.2018.03.017

WANG D D， XING G Z， YANG J H， et al. Dependence of energy transfer and photoluminescence on tailored defects in Eu-doped ZnO nanosheets-based microflowers ［J］. J. Alloys Compd.， 2010， 504（1）： 22-26. doi: 10.1016/j.jallcom.2010.05.105http://dx.doi.org/10.1016/j.jallcom.2010.05.105

THOOL G S， ARUNAKUMARI M， SINGH A K， et al. Shape tunable synthesis of Eu- and Sm- doped ZnO microstructures： a morphological evaluation ［J］. Bull. Mater. Sci.， 2015， 38（6）： 1519-1525. doi: 10.1007/s12034-015-0967-zhttp://dx.doi.org/10.1007/s12034-015-0967-z

AHMED M A M， MWANKEMWA B S， CARLESCHI E， et al. Effect of Sm doping ZnO nanorods on structural optical and electrical properties of Schottky diodes prepared by chemical bath deposition ［J］. Mater. Sci. Semicond. Process.， 2018， 79： 53-60. doi: 10.1016/j.mssp.2018.02.003http://dx.doi.org/10.1016/j.mssp.2018.02.003

HAN N， WU X F， CHAI L Y， et al. Counterintuitive sensing mechanism of ZnO nanoparticle based gas sensors ［J］. Sens. Actuators B： Chem.， 2010， 150（1）： 230-238. doi: 10.1016/j.snb.2010.07.009http://dx.doi.org/10.1016/j.snb.2010.07.009

AHMED M A， COETSEE L， MEYER W E， et al. Influence （Ce and Sm） co-doping ZnO nanorods on the structural， optical and electrical properties of the fabricated Schottky diode using chemical bath deposition ［J］. J. Alloys Compd.， 2019， 810： 151929-1-10. doi: 10.1016/j.jallcom.2019.151929http://dx.doi.org/10.1016/j.jallcom.2019.151929

崔葆，黄秋梅，戎西林，等. 开关式氧化锌量子点荧光探针制备及其特异性检测Cu2+应用［J］. 发光学报， 2022， 43（4）： 620-632. doi: 10.37188/cjl.20210408http://dx.doi.org/10.37188/cjl.20210408

CUI B， HUANG Q M， RONG X L， et al. Preparation of switchable ZnO-NH2 QDs fluorescent probe and its application in specific detection of Cu2+ ［J］. Chin. J. Lumin.， 2022， 43（4）： 620-632. （in Chinese）. doi: 10.37188/cjl.20210408http://dx.doi.org/10.37188/cjl.20210408

SINGH J， SINGH R C. Enhancement of optical， dielectric and transport properties of （Sm， V） co-doped ZnO system and structure-property correlations ［J］. Ceram. Int.， 2021， 47（8）： 10611-10627. doi: 10.1016/j.ceramint.2020.12.174http://dx.doi.org/10.1016/j.ceramint.2020.12.174

ZOU T， XING X X， YANG Y， et al. Water-soluble ZnO quantum dots modified by （3-aminopropyl）triethoxysilane： the promising fluorescent probe for the selective detection of Cu2+ ion in drinking water ［J］. J. Alloys Compd.， 2020， 825： 153904-1-11. doi: 10.1016/j.jallcom.2020.153904http://dx.doi.org/10.1016/j.jallcom.2020.153904

SUN L W， SHI H Q， LI W N， et al. Lanthanum-doped ZnO quantum dots with greatly enhanced fluorescent quantum yield ［J］. J. Mater. Chem.， 2012， 22（17）： 8221-8227. doi: 10.1039/c2jm00040ghttp://dx.doi.org/10.1039/c2jm00040g

TALLURI B， PRASAD E， THOMAS T. Impact of solvent on the formation and optical properties of digestively ripened， ultra-small （r<2 nm） copper oxide quantum dots ［J］. J. Mol. Liq.， 2018， 265： 771-778. doi: 10.1016/j.molliq.2018.05.069http://dx.doi.org/10.1016/j.molliq.2018.05.069

GHIMIRE S， BIJU V. Relations of exciton dynamics in quantum dots to photoluminescence， lasing， and energy harvesting ［J］. J. Photochem. Photobiol. C： Photochem. Rev.， 2018， 34： 137-151. doi: 10.1016/j.jphotochemrev.2018.01.004http://dx.doi.org/10.1016/j.jphotochemrev.2018.01.004

HARANATH D， SAHAI S， JOSHI A G， et al. Investigation of confinement effects in ZnO quantum dots ［J］. Nanotechnology， 2009， 20（42）： 425701-1-7. doi: 10.1088/0957-4484/20/42/425701http://dx.doi.org/10.1088/0957-4484/20/42/425701

MOGHADDAM E， YOUZBASHI A A， KAZEMZADEH A， et al. Photoluminescence investigation of ZnO quantum dots surface modified with silane coupling agent as a capping agent ［J］. J. Lumin.， 2015， 168： 158-162. doi: 10.1016/j.jlumin.2015.08.008http://dx.doi.org/10.1016/j.jlumin.2015.08.008

WANG Z Y， WANG X Y， ZHU X S， et al. Fabrication of non-destructive and enhanced electrochemiluminescence interface for reusable detection of cell-released dopamine ［J］. Sens. Actuators B： Chem.， 2019， 285： 438-444. doi: 10.1016/j.snb.2019.01.087http://dx.doi.org/10.1016/j.snb.2019.01.087

SHERVEDANI R K， AMINI A. Direct electrochemistry of dopamine on gold—Agaricus bisporus laccase enzyme electrode： characterization and quantitative detection ［J］. Bioelectrochemistry， 2012， 84： 25-31. doi: 10.1016/j.bioelechem.2011.10.004http://dx.doi.org/10.1016/j.bioelechem.2011.10.004

SCHÖNING M J， JACOBS M， MUCK A， et al. Amperometric PDMS/glass capillary electrophoresis-based biosensor microchip for catechol and dopamine detection ［J］. Sens. Actuators B： Chem.， 2005， 108（1-2）： 688-694. doi: 10.1016/j.snb.2004.11.032http://dx.doi.org/10.1016/j.snb.2004.11.032

QIN X， YUAN C L， SHI R， et al. Colorimetric detection of dopamine based on iodine-mediated etching of gold nanorods ［J］. Chin. J. Anal. Chem.， 2021， 49（1）： 60-67. doi: 10.1016/s1872-2040(20)60073-1http://dx.doi.org/10.1016/s1872-2040(20)60073-1

LI F， GAO J， LI Y J， et al. Selective and sensitive determination of celastrol in traditional Chinese medicine based on molecularly imprinted polymers modified Mn-doped ZnS quantum dots optosensing materials ［J］. Colloids Surf. B： Biointerfaces， 2020， 190： 110929-1-9. doi: 10.1016/j.colsurfb.2020.110929http://dx.doi.org/10.1016/j.colsurfb.2020.110929

HAGHANI S K， ENSAFI A A， KAZEMIFARD N， et al. Development of a selective and sensitive chlorogenic acid fluorimetric sensor using molecularly imprinted polymer ZnO quantum dots ［J］. IEEE Sens. J.， 2020， 20（11）： 5691-5697. doi: 10.1109/jsen.2020.2972040http://dx.doi.org/10.1109/jsen.2020.2972040

HE K， SHEN C， ZHU Y Q， et al. Stable luminescent CsPbI3 quantum dots passivated by （3-Aminopropyl）triethoxysilane ［J］. Langmuir， 2020， 36（34）： 10210-10217. doi: 10.1021/acs.langmuir.0c01688http://dx.doi.org/10.1021/acs.langmuir.0c01688

Views

121

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Preparation of a Novel Ratiometric Fluorescent Capillary-based pH Sensor

Construction of Fluorescence Probe Based on Carbon Dots Dual Emission Strategy and Ratio Detection of Copper Ions in Water

Design of NIR-Ⅱ Luminescent Materials and Applications in Brain Imaging

Synthesis of Highly Selective Copper Ion Probe and Its Application in Adsorption

Related Author

CUI Mei-jia

HUANG Qiu-mei

HUANG Wen-yi

RONG Xi-lin

ZHANG Guo-qiang

XU Panying

LI Tianyi

WANG Xiaohui

Related Institution

Department of Radiology， the Third Medical Centre， Chinese PLA General Hospital， Beijing 100039， China

Beijing Key Laboratory of Work Safety Intelligent Monitoring， School of Electronic Engineering， Beijing University of Posts and Telecommunications， Beijing 100876， China

School of Chemistry， Dalian University of Technology

State Key Laboratory of Rare Earth Resource Utilization，Changchun Institute of Applied Chemistry， Chinese Academy of Sciences

School of Applied Chemistry and Engineering， University of Science and Technology of China

Address：No.3888 Dong Nanhu Road, Changchun, Jilin, China Postal code：130033
Tel：0431-86176862 Email：fgxbt@126.com
Technical support is provided by Beijing Founder electronics co., LTD 吉ICP备11002662号-17 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰

Preparation of Water-soluble Sm∶ZnO-NH2 QDs Fluorescent Probe and Its Application for Selective Detection of Dopamine

DOI：10.37188/CJL.20220296

摘要

Abstract

关键词

Keywords

references

Preparation of Water-soluble Sm∶ZnO-NH₂ QDs Fluorescent Probe and Its Application for Selective Detection of Dopamine