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Research Progresses on Chemiluminescent Gold Nanoclusters Applied in Biological
增强出版in vitro Detection- Chinese Journal of Luminescence Vol. 43, Issue 3, Pages: 314-326(2022)
- 作者机构：
1.浙江大学材料科学与工程学院 硅材料国家重点实验室，浙江 杭州 310027
2.杭州安旭生物科技有限公司，浙江 杭州 310011
- 作者简介：
- 基金信息：“Lingyan” research and development project of Zhejiang Province(2022C01142)
DOI：10.37188/CJL.20210385
CLC： O482.31Published：2022-03，
Received：09 December 2021，
Revised：27 December 2021，
扫 描 看 全 文
Tian-hao XIA, Yun-peng WANG, Xiao-ru DAI, et al. Research Progresses on Chemiluminescent Gold Nanoclusters Applied in Biological
in vitro Detection. [J]. Chinese Journal of Luminescence 43(3):314-326(2022)Tian-hao XIA, Yun-peng WANG, Xiao-ru DAI, et al. Research Progresses on Chemiluminescent Gold Nanoclusters Applied in Biological
in vitro Detection. [J]. Chinese Journal of Luminescence 43(3):314-326(2022) DOI： 10.37188/CJL.20210385.
摘要
金纳米簇是一种制备工艺简单、具有分子级尺寸和量子效应的新型发光材料，近年来在化学发光检测中得到了广泛应用，特别是较多应用于体外生物检测。本文综述了金纳米簇化学发光(含电化学发光)体系在体外生物检测中的应用进展。首先，阐释了金纳米簇的合成方法、结构、性质及其化学发光基本原理；其次，总结了国内外近年来基于该体系的体外生物检测研究进展，并梳理了改善发光强度和检测灵敏度的已有策略；最后，对金纳米簇化学发光的未来发展趋势进行了展望。
Abstract
Gold nanoclusters are novel luminescent materials with simple preparation method
molecular size and quantum effect
which have been widely applied in chemiluminescence detection in recent years
especially in
in vitro
biological detection. This article reviews the progress of gold nanoclusters chemiluminescence(including electrochemiluminescence) system in the application of
in vitro
biological detection. First
the synthesis
structure
properties of gold nanoclusters and the basic principle of chemiluminescence system are introduced and explained theoretically. Next
recent reports are summarized on
in vitro
biological detection with gold nanoclusters
and strategies in literatures are overviewed and commented on how to improve the luminescent intensity and detection sensitivity. Finally
we give an outlook on the development trend of gold nanoclusters chemiluminescence system.
关键词
金纳米簇化学发光电化学发光体外生物检测
Keywords
gold nanoclusterschemiluminescenceelectrochemiluminescencein vitro biological detection
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