基于Schiff碱结构的香豆素类荧光探针的合成及对Mg2+的识别

杨文生; 杨菀; 马亚军

doi:10.3788/fgxb20194007.0941

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基于Schiff碱结构的香豆素类荧光探针的合成及对Mg²⁺的识别

发光学应用及交叉前沿 | 更新时间：2020-08-12

- 基于Schiff碱结构的香豆素类荧光探针的合成及对Mg²⁺的识别
- Synthesis of Coumarin Fluorescent Probe Based on Schiff Base Structure and Identification to Mg²⁺
- 发光学报 2019年40卷第7期页码：941-946
- 作者机构：
  
  榆林学院化学与化工学院,陕西榆林,719000
- 作者简介：
- 基金信息：
  
  国家自然科学基金（21763030）();榆林学院博士科研启动基金项目（16GK14）资助()
- DOI：10.3788/fgxb20194007.0941
  中图分类号： O657.39
- 纸质出版日期：2019-7-5，
  
  网络出版日期：2018-10-31，
  
  收稿日期：2018-7-9，
  
  修回日期：2018-10-24，
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杨文生, 杨菀, 马亚军. 基于Schiff碱结构的香豆素类荧光探针的合成及对Mg2+的识别[J]. 发光学报, 2019,40(7): 941-946

YANG Wen-sheng, YANG Wan, MA Ya-jun. Synthesis of Coumarin Fluorescent Probe Based on Schiff Base Structure and Identification to Mg2+[J]. Chinese Journal of Luminescence, 2019,40(7): 941-946
杨文生, 杨菀, 马亚军. 基于Schiff碱结构的香豆素类荧光探针的合成及对Mg2+的识别[J]. 发光学报, 2019,40(7): 941-946 DOI： 10.3788/fgxb20194007.0941.

YANG Wen-sheng, YANG Wan, MA Ya-jun. Synthesis of Coumarin Fluorescent Probe Based on Schiff Base Structure and Identification to Mg2+[J]. Chinese Journal of Luminescence, 2019,40(7): 941-946 DOI： 10.3788/fgxb20194007.0941.

摘要

以2-氨基苯并咪唑和7-羟基香豆素为基本原料制备了Mg

荧光探针，采用核磁共振谱与质谱等手段对产物的构成进行了详尽的表征。然后通过荧光发射光谱的测试分析，了解了探针的各项性能。结果显示，在MeOH:H

O=1:1（

）混合溶液中探针对Mg

具有良好的选择性而不受其他金属离子（Ca

、Na

、Li

、K

、Cu

、Fe

、Zn

、Ni

、Mn

、Ba

、Cd

、Cr

、Ag

、Al

、Hg

、Co

、Pb

）的干扰。探针对Mg

具有可逆性，其检测限为7.310

-8

mol/L。通过对探针的性能研究可知该探针能够完成对Mg

的检测，在生命医学、环境科学及分析化学等领域具有潜在的应用价值。

Abstract

The fluorescence probe for Mg

was prepared with 2-amino benzene and imidazole and 7-hydroxyl coumarin as the basic raw material. The product composition was characterized in detail by means of nuclear magnetic resonance spectrum and mass spectrum

and then through the test and analysis by fluorescence emission spectrum

the various properties of the probe were understood. The results showed that the probe has good selectivity to Mg

in the mixed solution of MeOH:H

O=1:1(

V:V

) and there are no other metal ions(Ca

) interference. The probe is reversible to Mg

the detection limit is 7.310

-8

mol/L. Through the study on performance of the probe

the probe can complete the detection of Mg

. The probe has potential application value in the fields of biomedical

environmental science and analytical chemistry

etc

关键词

香豆素荧光探针金属离子检测限

Keywords

coumarinfluorescent probemetal ionsdetection limit

references

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陈顺志,毛国春. 镁检测的方法及其临床意义[J]. 临床检验杂志, 1984,2(3):38-39. CHEN S Z,MAO G C. Magnesium detection methods and clinical significance[J]. J. Clin. Examinat.,1984,2(3):38-39. (in Chinese)

LIU Z,PENG C N,LU Z X, et al.. A novel fluorescent sensor derived from Benzimidazo[2,1-a]benz[de]isoquinoline-7-one-12-carboxylic acid for Cu2+,Cd2+ and PPi[J]. Dyes Pigments, 2015,123:85-91.

WENG L C,LEE N J,YEH W T, et al.. Lower intake of magnesium and dietary fiber increases the incidence of type 2 diabetes in Taiwanese[J]. J. Formos. Med. Assoc., 2012,111(11):651-659.

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