Fe3O4/CA@CQDs磁性荧光复合材料的制备及表征

董淑玲; 王胜男; 王秀玲; 刘勇健

doi:10.3788/fgxb20194004.0453

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Fe₃O₄/CA@CQDs磁性荧光复合材料的制备及表征

材料合成及性能 | 更新时间：2020-08-12

- Fe₃O₄/CA@CQDs磁性荧光复合材料的制备及表征
- Preparation and Characterization of Fe₃O₄/CA@CQDs Magnetic-fluorescent Composite
- 发光学报 2019年40卷第4期页码：453-458
- 作者机构：
  
  1. 苏州科技大学化学生物与材料工程学院,江苏苏州,215009
  2. 硅湖职业技术学院,江苏苏州,215332
- 作者简介：
- 基金信息：
  
  国家自然科学基金（411732302）;江苏省高校自然科学基金（13KJB150035）资助项目
- DOI：10.3788/fgxb20194004.0453
  中图分类号： O61;O482.31
- 纸质出版日期：2019-4-5，
  
  网络出版日期：2018-9-21，
  
  收稿日期：2018-6-14，
  
  修回日期：2018-8-28，
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董淑玲, 王胜男, 王秀玲等. Fe3O4/CA@CQDs磁性荧光复合材料的制备及表征[J]. 发光学报, 2019,40(4): 453-458

DONG Shu-ling, WANG Sheng-nan, WANG Xiu-ling etc. Preparation and Characterization of Fe3O4/CA@CQDs Magnetic-fluorescent Composite[J]. Chinese Journal of Luminescence, 2019,40(4): 453-458
董淑玲, 王胜男, 王秀玲等. Fe3O4/CA@CQDs磁性荧光复合材料的制备及表征[J]. 发光学报, 2019,40(4): 453-458 DOI： 10.3788/fgxb20194004.0453.

DONG Shu-ling, WANG Sheng-nan, WANG Xiu-ling etc. Preparation and Characterization of Fe3O4/CA@CQDs Magnetic-fluorescent Composite[J]. Chinese Journal of Luminescence, 2019,40(4): 453-458 DOI： 10.3788/fgxb20194004.0453.

摘要

为了制备出低毒且性能优异的磁性荧光复合材料，选用发光稳定且生物相容性高的碳量子点（CQDs）作为荧光探针，分别采用一步水热法和化学共沉淀法制备了荧光性能优异的CQDs和超顺磁性四氧化三铁（Fe

），再以生物相容性较好的柠檬酸（CA）修饰Fe

，得到表面富含功能性羟基和羧基的Fe

/CA，通过偶联剂乙二胺将CQDs与Fe

/CA连接，成功制得Fe

/CA@CQDs磁性荧光复合材料。并对其进行红外光谱（FTIR）、荧光光谱、振动样品磁强计（VSM）、X射线衍射仪（XRD）、荧光显微镜及透射电子显微镜（TEM）表征，结果表明:Fe

/CA@CQDs为核壳结构，粒径为30~40 nm，饱和磁化强度为20.14 Am

-1

，该双功能复合材料具有优良的荧光性能和磁性能，细胞毒性低且生物相容性高，有望取代传统荧光磁性纳米复合材料，并广泛应用于生物医学领域。

Abstract

For preparation of low toxicity and excellent magnetic-fluorescent composite material

carbon quantum dots(CQDs) with high light stability and biocompatibility were selected as fluorescent probe. The CQDs with excellent fluorescence were successfully synthesized by one-step hydrothermal method. Superparamagnetic nanoparticles Fe

were prepared by hydrothermal coprecipitation

which were modified by citric acid(CA) with good biocompatibility.Then Fe

/CA was formed and riched of functional hydroxyl and carboxylgroups. Through coupling agent ethylenediamine

the CQDs were connected with Fe

/CA for successful preparation of magnetic-fluorescent composite material Fe

/CA@CQDs. Fourier transform infrared spectroscopy(FTIR)

fluorescence spectrophotometer

vibrating sample magnetometer(VSM)

X-ray diffraction(XRD)

fluorescence microscope and transmission electron microscopy(TEM) were used for characterization. The results show that the Fe

/CA@CQDs possessed core shell structure with an average diameter of 30-40 nm and the saturation magnetic intensity 20.14 Am

-1

. Attributed to the excellent fluorescence properties and magnetic

low cytotoxicity and high biocompatibility

the bifunction composite material is expected to replace traditional magnetic-fluorescent nanocomposites and widely used in biomedical fields.

关键词

磁性荧光碳量子点复合材料

Keywords

magneticfluorescentcarbon quantum dotscomposite material

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