NaYF4∶Yb3+,Tm3+负载壳聚糖微球的制备及发光性质研究

张敬迎; 侯光辉; 石建军; 熊腾杰; 刘钟馨

doi:10.3788/fgxb20133402.0160

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NaYF₄∶Yb³⁺,Tm³⁺负载壳聚糖微球的制备及发光性质研究

半导体发光、激光和光电性质 | 更新时间：2020-08-12

- NaYF₄∶Yb³⁺,Tm³⁺负载壳聚糖微球的制备及发光性质研究
- Fabrication and Luminescent Property of NaYF₄∶Yb³⁺,Tm³⁺ Loaded Chitosan Microspheres
- 发光学报 2013年34卷第2期页码：160-164
- 作者机构：
  
  1. 海南大学热带岛屿资源先进材料教育部重点实验室,海南海口,570228
  2. 海南大学材料与化工学院,海南海口,570228
- 作者简介：
- 基金信息：
  
  海南省国际科技合作重点项目计划(GJXM201103)资助项目()
- DOI：10.3788/fgxb20133402.0160
  中图分类号： O611
- 纸质出版日期：2013-2-10，
  
  收稿日期：2012-10-29，
  
  修回日期：2012-12-3，
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张敬迎, 侯光辉, 石建军, 熊腾杰, 刘钟馨. NaYF4∶Yb3+,Tm3+负载壳聚糖微球的制备及发光性质研究[J]. 发光学报, 2013,34(2): 160-164

ZHANG Jing-ying, HOU Guang-hui, SHI Jian-jun, XIONG Teng-jie, LIU Zhong-xin. Fabrication and Luminescent Property of NaYF4∶Yb3+,Tm3+ Loaded Chitosan Microspheres[J]. Chinese Journal of Luminescence, 2013,34(2): 160-164
张敬迎, 侯光辉, 石建军, 熊腾杰, 刘钟馨. NaYF4∶Yb3+,Tm3+负载壳聚糖微球的制备及发光性质研究[J]. 发光学报, 2013,34(2): 160-164 DOI： 10.3788/fgxb20133402.0160.

ZHANG Jing-ying, HOU Guang-hui, SHI Jian-jun, XIONG Teng-jie, LIU Zhong-xin. Fabrication and Luminescent Property of NaYF4∶Yb3+,Tm3+ Loaded Chitosan Microspheres[J]. Chinese Journal of Luminescence, 2013,34(2): 160-164 DOI： 10.3788/fgxb20133402.0160.

摘要

采用溶剂热法合成了聚乙烯亚胺(PEI)修饰的NaYF

∶Yb

纳米晶。产物具有良好的结晶性

粒径分布均匀

可稳定分散在水溶液中。通过微乳法制备了NaYF

∶Yb

纳米晶负载壳聚糖微球。结果表明:纳米晶均匀地嵌在壳聚糖微球的表面壳层

球核为纯壳聚糖的交联产物。粗糙的球体表面使微球具有较好的分散性。在980 nm近红外光激发下

纳米晶负载壳聚糖微球具有良好的上转换发光特性

发光强度随纳米晶负载量的增加而增大

通过调控纳米晶的负载量可实现对纳米晶负载壳聚糖微球发光强度的调控。

Abstract

Upconversion nanocrystals have caused much attention

due to their superior optical and chemical properties. In this study

upconversion nanocrystals loaded chitosan microshperes were designed to develop the applications in biomedicine. Polyethyleneimine (PEI) modified NaYF

∶Yb

upconversion nanocrystals were prepared by solvothermal method. XRD and TEM indicated that the particles crystallized very well and the size was about 20 nm. The dispersity was enhanced

both in water and in chitosan solution. NaYF

∶Yb

loaded chitosan microshperes were fabricated using microemulsion method. SEM pictures showed that the chitosan microspheres' surface was rough and the NaYF

∶Yb

particles were embedded in the surface shell. For PEI and chitosan having the same positive charge

during the cross-linking process

PEI modified particles moved to the surface of the chitosan microshperes drived by repulsive force. The luminescence intensity of the NaYF

∶Yb

loaded chitosan microshperes increased with the increasing of nanopaticles. Due to the biocompatibility and biodegradability of the chitosan carrier

this material can improve the duration in vivo

avoid process release effect. This kind of nanocrystals loaded chitosan microshperes may have broad application prospects in photodynamic therapy

biological imaging

fluorescent identification

as controlled release materials.

关键词

溶剂热法上转换发光壳聚糖微球

Keywords

solvothermal synthesisupconversion fluorescencechitosan microshpere

references

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