光功能纳米材料与肿瘤光学治疗展望

刘庄; 冯良珠

doi:10.37188/CJL.20200320

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光功能纳米材料与肿瘤光学治疗展望

创刊40周年特别专栏——青稞论道 | 更新时间：2020-11-10

- 光功能纳米材料与肿瘤光学治疗展望
- Perspectives on Photo-functional Nanomaterials and Cancer Phototherapy
- 发光学报 2020年41卷第11期页码：1339-1342
- 作者机构：
  
  1.苏州大学功能纳米与软物质研究院, 江苏苏州 215123
- 作者简介：
  
  [ "刘庄(1982-)，男，湖南长沙人。2008年于美国斯坦福大学(Stanford University)获得化学博士学位；2008—2009年在斯坦福大学化学系以及医学院从事博士后研究；2009年6月加入苏州大学功能纳米与软物质研究院，被聘为教授，博士研究生导师。在纳米生物材料领域从事研究，近年来在纳米生物材料的设计构建、基于纳米技术的肿瘤微环境调控以及基于生物材料的肿瘤免疫治疗方面取得了一系列创新成果；共发表学术论文300余篇，论文总引用超过50 000次，H-index 125。2015年获得国家杰出青年基金资助，2018年入选长江学者特聘教授，2015年受邀成为英国皇家化学会会士(RSC Fellow)，2019年入选美国医学与生物工程学会会士(AIMBE Fellow)，2015—2019年连续入选汤森路透社(Thomson Reuters)发布的“全球高被引科学家”(Highly Cited Researchers)(化学、材料)，任生物材料领域国际著名期刊Biomaterials杂志副主编和多个国际主流期刊编委。E-mail: zliu@suda.edu.cn" ]
  [ "冯良珠 (1987-)，男，江苏宿迁人。2015年于苏州大学获得化学博士学位；2015—2016年在中国澳门大学中华医药研究院从事博士后研究；2016年11月加入苏州大学功能纳米与软物质研究院，被聘为助理研究员，2018年7月晋升为副研究员。近年来围绕仿生纳米生物材料的设计构建、肿瘤微环境调控与肿瘤联合治疗等方面开展研究。迄今，在Chem., J. Am. Chem. Soc., ACS Nano, Nano Lett., Adv. Funct. Mater., Biomaterials, Small等国际知名期刊上发表学术论文90余篇，他引11 300余次，H-index 44，2019年入选汤森路透社(Thomson Reuters)发布的“全球高被引科学家”(Highly Cited Researchers)。E-mail: lzfeng@suda.edu.cn" ]
- 基金信息：
  
  国家杰出青年科学基金(51525203)；国家重点研发计划(2016YFA0201200)；江苏省社会发展科技计划(BE2019658)；苏州纳米科技协同创新中心、高等
- DOI：10.37188/CJL.20200320
  中图分类号：
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刘庄, 冯良珠. 光功能纳米材料与肿瘤光学治疗展望[J]. 发光学报, 2020,41(11):1339-1342.

Zhuang LIU, Liang-zhu FENG. Perspectives on Photo-functional Nanomaterials and Cancer Phototherapy[J]. Chinese Journal of Luminescence, 2020,41(11):1339-1342.
刘庄, 冯良珠. 光功能纳米材料与肿瘤光学治疗展望[J]. 发光学报, 2020,41(11):1339-1342. DOI： 10.37188/CJL.20200320.

Zhuang LIU, Liang-zhu FENG. Perspectives on Photo-functional Nanomaterials and Cancer Phototherapy[J]. Chinese Journal of Luminescence, 2020,41(11):1339-1342. DOI： 10.37188/CJL.20200320.

摘要

近二十年来，光功能纳米材料因其具有优越的光热转化与光敏化能力而被广泛研究用于肿瘤光学治疗，并展现出了良好的临床转化潜力。本文结合作者自身的科研经历，展望了基于光功能纳米材料的肿瘤光学治疗在其未来的临床转化过程中所面临的挑战与机遇，倡导相关科学家直面制约肿瘤光学治疗临床转化的若干问题，共同推进肿瘤光学治疗在临床中的应用，早日造福广大肿瘤患者。

Abstract

In the past two decades, we have witnessed the fast advances of cancer phototherapy, which tightly relies on the development of a large variety of photo-functional nanomaterials with outstanding photothermal conversion or photosensitization capacities, and has showed great promising for future clinical translation. Based on our own experimental experiences, we herein offer our perspectives on the challenges and opportunities, which would be faced in the future clinical translation of such photo-functional nanomaterials mediated cancer phototherapy. We encourage the researchers in this field to dissolve these problems hindering the clinical translation of cancer phototherapy, and work together to promote their clinical translation, thereby benefiting the cancer patients in clinics.

关键词

光功能纳米材料肿瘤光学治疗肿瘤光热治疗肿瘤光动力治疗

Keywords

photo-functional nanomaterialscancer phototherapyphotothermal therapyphotodynamic therapy

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