定量光声层析成像的研究进展

孙正; 郑兰

doi:10.3788/fgxb20173809.1222

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定量光声层析成像的研究进展

发光学应用及交叉前沿 | 更新时间：2020-08-12

- 定量光声层析成像的研究进展
- Review on Progress of Quantitative Photoacoustic Tomography
- 发光学报 2017年38卷第9期页码：1222-1232
- 作者机构：
  
  华北电力大学电子与通信工程系,河北保定,071003
- 作者简介：
- 基金信息：
  
  国家自然科学基金（61372042）();中央高校基本科研业务费专项资金（2014ZD31）资助项目()
- DOI：10.3788/fgxb20173809.1222
  中图分类号： O439
- 纸质出版日期：2017-9-5，
  
  收稿日期：2017-3-24，
  
  修回日期：2017-4-27，
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孙正, 郑兰,. 定量光声层析成像的研究进展[J]. 发光学报, 2017,38(9): 1222-1232

SUN Zheng, ZHENG Lan,. Review on Progress of Quantitative Photoacoustic Tomography[J]. Chinese Journal of Luminescence, 2017,38(9): 1222-1232
孙正, 郑兰,. 定量光声层析成像的研究进展[J]. 发光学报, 2017,38(9): 1222-1232 DOI： 10.3788/fgxb20173809.1222.

SUN Zheng, ZHENG Lan,. Review on Progress of Quantitative Photoacoustic Tomography[J]. Chinese Journal of Luminescence, 2017,38(9): 1222-1232 DOI： 10.3788/fgxb20173809.1222.

摘要

光声层析（Photoacoustic tomography，PAT）成像结合了超声成像的高分辨率和光学成像的高对比度的优势，是一种新型的生物医学成像模式。PAT成像算法包含两个逆问题，即根据组织产生的光声信号构建初始声压分布图（即图像重建）以及在此基础上估算成像区域的光学特性参数。后者是一个非线性的不适定问题，通常称为定量光声层析（Quantitative photo-acoustic tomography，qPAT）成像。本文在介绍光声成像原理的基础上，对主要的qPAT算法进行综述，讨论各自的优势和不足，并对未来可能的发展方向进行展望。

Abstract

Photoacoustic tomography (PAT)

an emerging medical imaging modality

combines the high resolution of ultrasonic imaging and high contrast of optical imaging. Current research on PAT includes two inverse problems

constructing the distribution of initial acoustic pressures according to the photo-acoustic signals generated by the tissues and estimating the optical absorption and scattering coefficients of the tissues within the imaging region based on the results of the first inversion. The latter

known as quantitative photoacoustic tomography (qPAT)

is in general a nonlinear ill-posed problem. This paper summarizes current algorithms for solving the qPAT inversion. Related advantages and limits as well as perspective studies are discussed.

关键词

定量光声成像图像重建逆问题光吸收系数散射系数Gruneisen系数

Keywords

quantitative photoacoustic tomography (qPAT)image reconstructioninverse problemoptical absorption coefficientdiffusion coefficientGruneisen coefficient

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