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1.内蒙古师范大学 化学与环境科学学院,内蒙古 呼和浩特 010022
2.内蒙古大学 化学化工学院,内蒙古精细有机合成重点实验室,内蒙古 呼和浩特 010021
[ "温雪菲(1996-),女,内蒙古达拉特旗人,硕士研究生,2019年于集宁师范学院获得学士学位,主要从事有机发光材料的合成及性能的研究。E-mail: 1097560502@qq.com" ]
[ "莎仁(1963-),女,内蒙古呼和浩特人,学士,教授,硕士生导师,1985年于内蒙古师范大学获得学士学位,主要从事发光材料、光致变色材料的设计合成及应用的研究。E-mail: sr@imnu.edu.cn" ]
[ "王建国(1982-),男,内蒙古兴和人,博士,教授,博士生导师,2014年于中国科学院化学研究所获得博士学位,主要从事有机光电功能材料的研究。E-mail: wangjg@iccas.ac.cn" ]
收稿日期:2022-01-17,
修回日期:2022-02-04,
纸质出版日期:2022-05
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温雪菲, 莎仁, 王建国. 刺激响应型AIE水凝胶研究进展[J]. 发光学报, 2022,43(5):642-661.
Xue-fei WEN, Ren SHA, Jian-guo WANG. Research Progress of Stimuli-responsive AIE-active Hydrogels[J]. Chinese journal of luminescence, 2022, 43(5): 642-661.
温雪菲, 莎仁, 王建国. 刺激响应型AIE水凝胶研究进展[J]. 发光学报, 2022,43(5):642-661. DOI: 10.37188/CJL.20220023.
Xue-fei WEN, Ren SHA, Jian-guo WANG. Research Progress of Stimuli-responsive AIE-active Hydrogels[J]. Chinese journal of luminescence, 2022, 43(5): 642-661. DOI: 10.37188/CJL.20220023.
刺激响应水凝胶可以对环境的微小变化产生较大的物理化学变化,在药物传递、生物分离、生物传感器和组织工程等领域具有广泛的应用。但受聚集导致荧光猝灭(ACQ)效应的影响,其在发光相关领域的应用受到限制,聚集诱导发光(AIE)概念的提出解决了这一难题。将AIE分子引入水凝胶体系,获得刺激响应型AIE水凝胶,在生物医学、信息防伪、3D水凝胶驱动器以及软体机器人的开发等多个高科技领域崭露头角。本文将近年来报道的刺激响应型AIE水凝胶按刺激因素分为物理因素(温度和光)、化学因素(pH、溶剂和离子)和生物因素(酶)三大类,分别阐述了水凝胶的制备、响应机理及潜在应用,并针对刺激响应型AIE水凝胶面临的问题和挑战进行了展望。
Stimulus-responsive hydrogels
which can undergo physical and/or chemical changes in response to the minor variations in the environment
are widely applied in the fields of drug delivery
bioseparation
biosensors and tissue engineering. However
due to the aggregation-caused quenching(ACQ) of fluorescence
their applications in luminescence-related fields are extremely limited. Fortunately
aggregation-induced emission(AIE) phenomena perfectly resolved the problem. By incorporating fluorophores with AIE feature into hydrogels
stimuli-responsive AIE-active hydrogels can be obtained. And they have cut a figure in several high-tech fields including biomedical
information anti-counterfeiting
3D hydrogel actuators and soft robots. In this article
we summarized and classified the recently reported stimuli-responsive AIE-active hydrogels into three categories: those are responsive to physical(temperature and light)
chemical(pH
solvent and ion type) and biological(enzyme) stimulus. The preparation
responsive mechanism and applications of these stimuli-responsive AIE-active hydrogels were described respectively. And finally
the problems and challenges faced by stimuli-responsive AIE-active hydrogels are also prospected.
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