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适用于近红外荧光/核磁双模成像的GdF3∶Nd3+,Yb3+@NaGdF4纳米材料
增强出版GdF3∶Nd3+,Yb3+@NaGdF4 Nanomaterials for Near Infrared Fluorescence and Magnetic Resonance Dual-mode Imaging
- 发光学报 2022年43卷第3期 页码：350-358
- 作者机构：
河北大学 物理科学与技术学院，河北 保定 071002
- 作者简介：
[ "何旭(1995-)，男，河北廊坊人，硕士研究生，2019年于河北大学获得学士学位，主要从事稀土掺杂发光材料的研究。E-mail: 18830285787@163.com" ]
[ "李旭(1978-)，男，河北石家庄人，博士，研究员，2016年于北京交通大学获得博士学位，主要从事稀土发光材料方面的研究。E-mail: lixcn@sina.com" ]
[ "王凤和(1983-)，女，河北沧州人，博士，讲师，2017年于新加坡国立大学获得博士学位，主要从事稀土发光材料方面的研究。E-mail: fenghe_wang@hotmail.com" ]
- 基金信息：河北省自然科学基金(F2019201316);国家自然科学基金(51802069);中央引导地方项目(216Z104G);河北大学人才引进项目(521000981236);河北大学研究生创新项目(HUB2021ss066)
DOI：10.37188/CJL.20210391
中图分类号： O482.31纸质出版日期：2022-03，
收稿日期：2021-12-13，
修回日期：2021-12-29，
- 稿件说明：
移动端阅览
何旭, 吴亚楠, 蒋越宁, 等. 适用于近红外荧光/核磁双模成像的GdF3∶Nd3+,Yb3+@NaGdF4纳米材料[J]. 发光学报, 2022,43(3):350-358.
XU HE, YA-NAN WU, YUE-NING JIANG, et al. GdF3∶Nd3+,Yb3+@NaGdF4 Nanomaterials for Near Infrared Fluorescence and Magnetic Resonance Dual-mode Imaging. [J]. Chinese journal of luminescence, 2022, 43(3): 350-358.
何旭, 吴亚楠, 蒋越宁, 等. 适用于近红外荧光/核磁双模成像的GdF3∶Nd3+,Yb3+@NaGdF4纳米材料[J]. 发光学报, 2022,43(3):350-358. DOI： 10.37188/CJL.20210391.
XU HE, YA-NAN WU, YUE-NING JIANG, et al. GdF3∶Nd3+,Yb3+@NaGdF4 Nanomaterials for Near Infrared Fluorescence and Magnetic Resonance Dual-mode Imaging. [J]. Chinese journal of luminescence, 2022, 43(3): 350-358. DOI： 10.37188/CJL.20210391.
摘要
利用Nd
3+
与Yb
3+
之间的能量传递，设计了808 nm激发下具有近红外光致发光的GdF
3
∶Nd
3+
Yb
3+
@NaGdF
4
磁性纳米探针。通过合成参数调控，研究了反应时间和前驱物浓度对GdF
3
∶Nd
3+
Yb
3+
材料形貌的影响。GdF
3
∶Nd
3+
Yb
3+
在808 nm激发下在近红外(NIR)第一/第二窗口具有较宽的发射峰(970~1 070 nm)，共掺杂体系实现了Yb
3+
和Nd
3+
双发光中心发光，有效提高了近红外区间的发光性能，同时克服了用980 nm激发的荧光成像引起生物组织过热的缺点。表面包覆NaGdF
4
惰性壳可以进一步提高GdF
3
∶Nd
3+
Yb
3+
的近红外发光强度，研究了不同厚度NaGdF
4
惰性壳对GdF
3
∶Nd
3+
Yb
3+
发光增强的影响。由于Gd
3+
具有的顺磁特性，GdF
3
∶Nd
3+
Yb
3+
@NaGdF
4
显示出顺磁性能，磁化值为0.45 A·m
2
/kg，适合作为磁共振成像(MRI)T1探针。GdF
3
∶Nd
3+
Yb
3+
@NaGdF
4
纳米颗粒在NIR荧光成像和MRI领域具有广阔的应用前景。
Abstract
GdF
3
∶Nd
3+
Yb
3+
magnetic nanocomposites with near-infrared photoluminescence under 808 nm excitation were designed based on the energy transfer between Nd
3+
and Yb
3+
. The influence of synthesis parameters on the morphology of GdF
3
∶Nd
3+
Yb
3+
was discussed. The obtained GdF
3
∶Nd
3+
Yb
3+
exhibits a wide emission band(970-1 070 nm) under 808 nm excitation. The co-doping system of Nd
3+
and Yb
3+
can realize the dual emission center of Yb
3+
and Nd
3+
as the emission center. It effectively improves the luminescence performance in the near-infrared region and overcomes the disadvantage of overheating biological tissues by fluorescence imaging under 980 nm excitation. An inert shell of NaGdF
4
was grown on GdF
3
∶Nd
3+
Yb
3+
surface
which could improve the emission intensity dramatically. Meanwhile
the effect of NaGdF
4
inter shell with different thicknesses on the luminescence enhancement of GdF
3
∶Nd
3+
Yb
3+
was studied. The final products GdF
3
∶Nd
3+
Yb
3+
@NaGdF
4
are paramagnetic with magnetization 0.45 A·m
2
/kg. This indicates that GdF
3
∶Nd
3+
Yb
3+
@NaGdF
4
has broad application prospects in both the fluorescence imaging field and magnetic resonance imaging(MRI) field.
关键词
近红外能量传递磁共振成像
Keywords
near-infraredenergy transfermagnetic resonance imaging
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