CdTe和CdTe/CdS量子点与叶酸分子荧光相互作用
增强出版Fluorescence Interaction Between Folate Molecules and CdTe and CdTe/CdS Quantum Dots
- 发光学报 2021年42卷第12期 页码：1944-1950
- 作者机构：
1.天津城建大学 理学院，天津 300384
2.中企众鑫(天津)工业设计有限公司，天津 300384
- 作者简介：
[ "李光旻(1979-)，男，天津人，博士，副教授，2015年于南开大学获得博士学位，主要从事无机手性量子点及荧光探针的研究。E-mail: 504753199@qq.com" ]
[ "刘淏洋(2000-)，男，四川攀枝花人，在读本科生，主要从事量子点荧光相互作用的研究。E-mail: tauceti@foxmail.com" ]
[ "刘洪飞(1985-)，男，河北任丘人，博士，讲师，2013年于中国科学院半导体研究所获得博士学位，主要从事半导体材料掺杂改性方面的计算研究。E-mail: liuhongfei001@163.com" ]
- 基金信息：国家自然科学基金(51578360;51778398);天津市高等学校基本科研业务资助项目(170401017);天津市技术创新引导专项（基金）(21YDTPJC00970)
DOI：10.37188/CJL.20210257
中图分类号：
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李光旻, 刘淏洋, 杨洋, 等. CdTe和CdTe/CdS量子点与叶酸分子荧光相互作用[J]. 发光学报, 2021,42(12):1944-1950.
Guang-min LI, Hao-yang LIU, Yang YANG, et al. Fluorescence Interaction Between Folate Molecules and CdTe and CdTe/CdS Quantum Dots[J]. Chinese Journal of Luminescence, 2021,42(12):1944-1950.
李光旻, 刘淏洋, 杨洋, 等. CdTe和CdTe/CdS量子点与叶酸分子荧光相互作用[J]. 发光学报, 2021,42(12):1944-1950. DOI： 10.37188/CJL.20210257.
Guang-min LI, Hao-yang LIU, Yang YANG, et al. Fluorescence Interaction Between Folate Molecules and CdTe and CdTe/CdS Quantum Dots[J]. Chinese Journal of Luminescence, 2021,42(12):1944-1950. DOI： 10.37188/CJL.20210257.
摘要
制备了水溶性半胱氨酸修饰的CdTe和CdTe/CdS核壳结构量子点，实现了对叶酸分子的特异性荧光标记，可作为具有应用潜力的叶酸浓度快速测定荧光探针。实验结果表明，叶酸分子可以使CdTe量子点发生明显的荧光猝灭，而在CdTe/CdS核壳结构量子点中，没有观察到这种猝灭行为。本文采用Stern-Volmer方程对荧光猝灭机制进行了分析，研究表明该猝灭机制是静态荧光猝灭。CdTe量子点在与叶酸分子作用过程中，荧光光谱发射峰发生了约35 nm的蓝移，热力学计算表明，量子点可能与叶酸分子通过静电作用形成了络合结构。
Abstract
Water soluble cysteine modified CdTe and CdTe/CdS core-shell quantum dots were prepared, which can realize the specific fluorescent labeling of folate molecules, and function as a fluorescent probe for detecting the concentration of folate. The experimental results showed that folate can cause obvious fluorescence quenching of CdTe quantum dots, but this quenching behavior was not observed in CdTe/CdS core-shell system. The fluorescence quenching mechanism was analyzed by Stern-Volmer equation, and the research showed that it was a static fluorescence quenching mechanism. The fluorescence emission spectrum had a blue shift of about 35 nm in the interaction between CdTe quantum dots and folate molecules. Thermodynamic calculation showed that a complex structure may be formed through electrostatic interaction between the quantum dots and folate molecules.
关键词
荧光量子点叶酸猝灭CdTeCdTe/CdS核壳结构
Keywords
fluorescencequantum dotsfolatequenchingCdTeCdTe/CdS core-shell structure
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