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长春工业大学 化学与生命科学学院,材料科学高等研究院,吉林 长春 130012
[ "郑敏(1978-),女,河南郑州人,博士,教授,博士研究生导师,2007年于中国科学院长春应用化学研究所获得博士学位,主要从事碳点、有机功能染料和金属有机骨架材料在生物荧光探针、癌症的智能化靶向成像和精准治疗等领域应用的研究。E-mail: zhengm@ciac.ac.cn" ]
纸质出版日期:2021-08-01,
收稿日期:2021-04-30,
修回日期:2021-05-25,
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郑敏, 刘坤梅, 苏雅. 碳点在生物医学领域中的应用[J]. 发光学报, 2021,42(8):1233-1244.
Min ZHENG, Kun-mei LIU, Ya SU. Carbon Dots for Biomedical Applications[J]. Chinese Journal of Luminescence, 2021,42(8):1233-1244.
郑敏, 刘坤梅, 苏雅. 碳点在生物医学领域中的应用[J]. 发光学报, 2021,42(8):1233-1244. DOI: 10.37188/CJL.20210162.
Min ZHENG, Kun-mei LIU, Ya SU. Carbon Dots for Biomedical Applications[J]. Chinese Journal of Luminescence, 2021,42(8):1233-1244. DOI: 10.37188/CJL.20210162.
碳点作为新兴的碳纳米材料之一,由于具有低细胞毒性、强亲水性、良好的生物相容性、优异的光稳定性、可调的发光和易于修饰等独特的理化特性,在生物医学领域具有广泛的应用前景。本综述主要阐述了碳点在生物成像、药物/染料/蛋白/基因的递送和癌症诊断治疗等方面的应用,并探讨了其在生物医学领域应用的当前挑战和未来前景。
As one of the emerging carbon nanomaterials
carbon dots(CDs) have a wide application in biomedical field because of their unique physical and chemical properties such as low cytotoxicity
strong hydrophilicity
good biocompatibility
excellent photostability
adjustable luminescence and easy modification. In this review
we mainly discuss the applications of CDs in biological imaging
drug/dye/protein/gene delivery and cancer diagnosis and treatment. Furthermore
we discuss the current challenges and future prospects of CDs in biomedical applications.
碳点生物成像药物递送癌症诊断治疗
carbon dotsbioimagingdrug deliverycancer theranostic
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