聚乙烯吡咯烷酮修饰的NaYF4∶Yb3+/Er3+上转换 发光纳米粒子的制备及其生物兼容性

芦志华; 陈欢; 何春凤; 揣晓红; 秦冠仕; 赵丹

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聚乙烯吡咯烷酮修饰的NaYF₄∶Yb³⁺/Er³⁺上转换发光纳米粒子的制备及其生物兼容性

材料合成及性能研究 | 更新时间：2020-08-12

- 聚乙烯吡咯烷酮修饰的NaYF₄∶Yb³⁺/Er³⁺上转换发光纳米粒子的制备及其生物兼容性
- Synthesis of Water Soluble Upconversion NaYF₄∶Yb³⁺,Er³⁺ Nanoparticals Using Polyvinylpyrrolidone as Surfactant and Their Biological Compatibility
- 发光学报 2011年32卷第10期页码：993-997
- 作者机构：
  
  1. 吉林大学电子科学与工程学院集成光电子国家重点联合实验室
  2. 吉林大学第一医院泌尿外科
- 作者简介：
- 基金信息：
  
  吉林省科技发展计划(201105004,20100702,20100136)();吉林大学杰出青年科学基金(201005008)();吉林大学基本科研(20090307
- DOI：
  中图分类号： O482.31
- 收稿：2011-06-25，
  
  修回：2011-7-16，
  
  网络首发：2011-10-22，
  
  纸质出版：2011-10-22
- 稿件说明：
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芦志华, 陈欢, 何春凤, 揣晓红, 秦冠仕, 赵丹. 聚乙烯吡咯烷酮修饰的NaYF4∶Yb3+/Er3+上转换发光纳米粒子的制备及其生物兼容性[J]. 发光学报, 2011,32(10): 993-997

LU Zhi-hua, CHEN Huan, HE Chun-feng, CHUAI Xiao-hong, QIN Guan-shi, ZHAO Dan. Synthesis of Water Soluble Upconversion NaYF4∶Yb3+,Er3+ Nanoparticals Using Polyvinylpyrrolidone as Surfactant and Their Biological Compatibility[J]. Chinese Journal of Luminescence, 2011,32(10): 993-997
芦志华, 陈欢, 何春凤, 揣晓红, 秦冠仕, 赵丹. 聚乙烯吡咯烷酮修饰的NaYF4∶Yb3+/Er3+上转换发光纳米粒子的制备及其生物兼容性[J]. 发光学报, 2011,32(10): 993-997 DOI：

LU Zhi-hua, CHEN Huan, HE Chun-feng, CHUAI Xiao-hong, QIN Guan-shi, ZHAO Dan. Synthesis of Water Soluble Upconversion NaYF4∶Yb3+,Er3+ Nanoparticals Using Polyvinylpyrrolidone as Surfactant and Their Biological Compatibility[J]. Chinese Journal of Luminescence, 2011,32(10): 993-997 DOI：

摘要

以聚乙烯吡咯烷酮(PVP)为表面活性剂

利用溶剂热法合成了NaYF

∶20%Yb

3%Er

(摩尔分数)的上转换发光纳米粒子。利用扫描电子显微镜对粒子的形貌进行了表征

结果表明纳米颗粒的尺寸在30~40 nm

分布比较均匀。在980 nm红外光的激发下

样品能够发出肉眼可见的明亮的黄色上转换荧光。样品可以较好地分散在水溶液中形成透明澄清的溶液。利用MTT实验测量了不同给药浓度下NaYF

纳米粒子是否对HeLa细胞具有生物毒性。结果表明:PVP修饰的NaYF

∶Yb

/Er

上转换发光纳米粒子具有较好的生物兼容性

对HeLa细胞无生物毒性

在生物荧光标记领域具有潜在的应用价值。

Abstract

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references

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