钇(Ⅲ)-环丙沙星配合物的荧光性质及其应用

孙春燕; 平 红; 李宏坤; 李永吉

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钇(Ⅲ)-环丙沙星配合物的荧光性质及其应用

论文 | 更新时间：2020-08-12

- 钇(Ⅲ)-环丙沙星配合物的荧光性质及其应用
- The Fluorescence Characteristic of Yttrium (Ⅲ)-ciprofloxacin Complex and Its Application
- 发光学报 2010年31卷第5期页码：646-650
- 作者机构：
  
  吉林大学军需科技学院,吉林长春,130062
- 作者简介：
- 基金信息：
  
  国家自然科学青年基金(20905031)();吉林大学引进优秀人才科研基金(4305050102H6)资助项目()
- DOI：
  中图分类号： O657.3;O482.31
- 纸质出版日期：2010-9-21，
  
  网络出版日期：2010-9-21，
  
  收稿日期：2009-12-29，
  
  修回日期：2010-3-10，
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孙春燕, 平红, 李宏坤, 李永吉. 钇(Ⅲ)-环丙沙星配合物的荧光性质及其应用[J]. 发光学报, 2010,31(5): 646-650

SUN Chun-yan, PING Hong, LI Hong-kun, LI Yong-ji. The Fluorescence Characteristic of Yttrium (Ⅲ)-ciprofloxacin Complex and Its Application[J]. 发光学报, 2010,31(5): 646-650
孙春燕, 平红, 李宏坤, 李永吉. 钇(Ⅲ)-环丙沙星配合物的荧光性质及其应用[J]. 发光学报, 2010,31(5): 646-650 DOI：

SUN Chun-yan, PING Hong, LI Hong-kun, LI Yong-ji. The Fluorescence Characteristic of Yttrium (Ⅲ)-ciprofloxacin Complex and Its Application[J]. 发光学报, 2010,31(5): 646-650 DOI：

摘要

研究了稀土钇离子(Y

)与环丙沙星(CPLX)体系的荧光特性

可使体系的荧光强度明显增强

由此建立测定环丙沙星药物的新方法。对CPLX-Y

体系荧光增强的机理进行了初步探讨

并系统研究了CPLX-Y

体系荧光强度的影响因素。在pH=5.5的Tris-HC1缓冲溶液中

浓度为5.010

-5

mol/L时

环丙沙星的浓度与体系的荧光强度呈良好的线性关系

线性范围为1.010

-9

~2.010

-6

mol/L

检出限为3.110

-11

mol/L(S/N=3)。该方法可用于人体尿药浓度和环丙沙星片剂的直接测定。

Abstract

The fluorescence characteristic of the CPLX-Y

complex system was studied in this article. Y

can significantly enhance the fluorescence intensity of the system

and accordingly we established a new sensitive analytical method to determine ciprofloxacin. The influencing factors of the CPLX-Y

fluorescence intensity were thoroughly studied

and the fluorescence enhancement mechanism was preliminary discussed. In the buffer solution of tris-HCl (pH=5.5) with 5.0 10

-5

mol /L of Y

the concentration of CPLX and fluorescence intensity of the system showed good linear relationship. The linear range is 1.010

-9

~2.0 10

-6

mol/L

and the detection limit is 3.110

-11

mol/L(S/N=3). This method can be directly used to determine the CPLX of human urine and CPLX tablet.

关键词

钇(Ⅲ)离子环丙沙星(CPLX)荧光尿样片剂

Keywords

yttrium (Ⅲ)ciprofloxacin (CPLX)fluorescenceurinetablet

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