刺激响应型AIE水凝胶研究进展

温雪菲; 莎仁; 王建国

doi:10.37188/CJL.20220023

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刺激响应型AIE水凝胶研究进展

特邀综述 | 更新时间：2022-05-23

- 刺激响应型AIE水凝胶研究进展
  增强出版
- Research Progress of Stimuli-responsive AIE-active Hydrogels
- 发光学报 2022年43卷第5期页码：642-661
- 作者机构：
  
  1.内蒙古师范大学　化学与环境科学学院，内蒙古　呼和浩特　010022
  2.内蒙古大学　化学化工学院，内蒙古精细有机合成重点实验室，内蒙古　呼和浩特　010021
- 作者简介：
  
  [ "温雪菲(1996-)，女，内蒙古达拉特旗人，硕士研究生，2019年于集宁师范学院获得学士学位，主要从事有机发光材料的合成及性能的研究。E-mail: 1097560502@qq.com" ]
  [ "莎仁(1963-)，女，内蒙古呼和浩特人，学士，教授，硕士生导师，1985年于内蒙古师范大学获得学士学位，主要从事发光材料、光致变色材料的设计合成及应用的研究。E-mail: sr@imnu.edu.cn" ]
  [ "王建国(1982-)，男，内蒙古兴和人，博士，教授，博士生导师，2014年于中国科学院化学研究所获得博士学位，主要从事有机光电功能材料的研究。E-mail: wangjg@iccas.ac.cn" ]
- 基金信息：
  
  国家自然科学基金(22165020;22161034;21871060);内蒙古自治区草原英才;内蒙古自治区科技攻关计划(2021GG0154);内蒙古自治区自然科学基金(2020JQ02;2020MS02004);内蒙古大学青年科技人才成长计划(21221505);江西省自然科学基金(20192BCBL23013)
- DOI：10.37188/CJL.20220023
  中图分类号： O482.31
- 纸质出版日期：2022-05，
  
  收稿日期：2022-01-17，
  
  修回日期：2022-02-04，
扫描看全文
温雪菲, 莎仁, 王建国. 刺激响应型AIE水凝胶研究进展[J]. 发光学报, 2022,43(5):642-661.

Xue-fei WEN, Ren SHA, Jian-guo WANG. Research Progress of Stimuli-responsive AIE-active Hydrogels[J]. Chinese Journal of Luminescence, 2022,43(5):642-661.
温雪菲, 莎仁, 王建国. 刺激响应型AIE水凝胶研究进展[J]. 发光学报, 2022,43(5):642-661. DOI： 10.37188/CJL.20220023.

Xue-fei WEN, Ren SHA, Jian-guo WANG. Research Progress of Stimuli-responsive AIE-active Hydrogels[J]. Chinese Journal of Luminescence, 2022,43(5):642-661. DOI： 10.37188/CJL.20220023.

摘要

刺激响应水凝胶可以对环境的微小变化产生较大的物理化学变化，在药物传递、生物分离、生物传感器和组织工程等领域具有广泛的应用。但受聚集导致荧光猝灭（ACQ）效应的影响，其在发光相关领域的应用受到限制，聚集诱导发光（AIE）概念的提出解决了这一难题。将AIE分子引入水凝胶体系，获得刺激响应型AIE水凝胶，在生物医学、信息防伪、3D水凝胶驱动器以及软体机器人的开发等多个高科技领域崭露头角。本文将近年来报道的刺激响应型AIE水凝胶按刺激因素分为物理因素（温度和光）、化学因素（pH、溶剂和离子）和生物因素（酶）三大类，分别阐述了水凝胶的制备、响应机理及潜在应用，并针对刺激响应型AIE水凝胶面临的问题和挑战进行了展望。

Abstract

Stimulus-responsive hydrogels

which can undergo physical and/or chemical changes in response to the minor variations in the environment

are widely applied in the fields of drug delivery

bioseparation

biosensors and tissue engineering. However

due to the aggregation-caused quenching(ACQ) of fluorescence

their applications in luminescence-related fields are extremely limited. Fortunately

aggregation-induced emission(AIE) phenomena perfectly resolved the problem. By incorporating fluorophores with AIE feature into hydrogels

stimuli-responsive AIE-active hydrogels can be obtained. And they have cut a figure in several high-tech fields including biomedical

information anti-counterfeiting

3D hydrogel actuators and soft robots. In this article

we summarized and classified the recently reported stimuli-responsive AIE-active hydrogels into three categories: those are responsive to physical(temperature and light)

chemical(pH

solvent and ion type) and biological(enzyme) stimulus. The preparation

responsive mechanism and applications of these stimuli-responsive AIE-active hydrogels were described respectively. And finally

the problems and challenges faced by stimuli-responsive AIE-active hydrogels are also prospected.

关键词

刺激响应型水凝胶聚集诱导发光信息防伪软体机器人药物传递

Keywords

stimuli-responsive hydrogelsaggregation-induced emissioninformation anti-counterfeitingsoft robotsdrug delivery

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