Research Progress of Stimuli-responsive AIE-active Hydrogels

Xue-fei WEN; Ren SHA; Jian-guo WANG

doi:10.37188/CJL.20220023

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Research Progress of Stimuli-responsive AIE-active Hydrogels

Invited Review | 更新时间：2022-05-23

- Research Progress of Stimuli-responsive AIE-active Hydrogels
  增强出版
- Chinese Journal of Luminescence Vol. 43, Issue 5, Pages: 642-661(2022)
- 作者机构：
  
  1.内蒙古师范大学　化学与环境科学学院，内蒙古　呼和浩特　010022
  2.内蒙古大学　化学化工学院，内蒙古精细有机合成重点实验室，内蒙古　呼和浩特　010021
- 作者简介：
- 基金信息：
  
  National Natural Science Foundation of China(22165020;22161034;21871060);Grassland Talent Program of Inner Mongolia Autonomous Region of China;Science and Technology Program of Inner Mongolia(2021GG0154);the Natural Science Foundation of Inner Mongolia Autonomous Region of China(2020JQ02;2020MS02004);Young Science and Technology Talents Cultivation Project of Inner Mongolia University(21221505);the Natural Science Foundation of Jiangxi Province(20192BCBL23013)
- DOI：10.37188/CJL.20220023
  CLC： O482.31
- Published：2022-05，
  
  Received：17 January 2022，
  
  Revised：04 February 2022，
- 稿件说明：
移动端阅览
XUE-FEI WEN, REN SHA, JIAN-GUO WANG. Research Progress of Stimuli-responsive AIE-active Hydrogels. [J]. Chinese journal of luminescence, 2022, 43(5): 642-661.
DOI：

XUE-FEI WEN, REN SHA, JIAN-GUO WANG. Research Progress of Stimuli-responsive AIE-active Hydrogels. [J]. Chinese journal of luminescence, 2022, 43(5): 642-661. DOI： 10.37188/CJL.20220023.

摘要

刺激响应水凝胶可以对环境的微小变化产生较大的物理化学变化，在药物传递、生物分离、生物传感器和组织工程等领域具有广泛的应用。但受聚集导致荧光猝灭（ACQ）效应的影响，其在发光相关领域的应用受到限制，聚集诱导发光（AIE）概念的提出解决了这一难题。将AIE分子引入水凝胶体系，获得刺激响应型AIE水凝胶，在生物医学、信息防伪、3D水凝胶驱动器以及软体机器人的开发等多个高科技领域崭露头角。本文将近年来报道的刺激响应型AIE水凝胶按刺激因素分为物理因素（温度和光）、化学因素（pH、溶剂和离子）和生物因素（酶）三大类，分别阐述了水凝胶的制备、响应机理及潜在应用，并针对刺激响应型AIE水凝胶面临的问题和挑战进行了展望。

Abstract

Stimulus-responsive hydrogels

which can undergo physical and/or chemical changes in response to the minor variations in the environment

are widely applied in the fields of drug delivery

bioseparation

biosensors and tissue engineering. However

due to the aggregation-caused quenching(ACQ) of fluorescence

their applications in luminescence-related fields are extremely limited. Fortunately

aggregation-induced emission(AIE) phenomena perfectly resolved the problem. By incorporating fluorophores with AIE feature into hydrogels

stimuli-responsive AIE-active hydrogels can be obtained. And they have cut a figure in several high-tech fields including biomedical

information anti-counterfeiting

3D hydrogel actuators and soft robots. In this article

we summarized and classified the recently reported stimuli-responsive AIE-active hydrogels into three categories: those are responsive to physical(temperature and light)

chemical(pH

solvent and ion type) and biological(enzyme) stimulus. The preparation

responsive mechanism and applications of these stimuli-responsive AIE-active hydrogels were described respectively. And finally

the problems and challenges faced by stimuli-responsive AIE-active hydrogels are also prospected.

关键词

刺激响应型水凝胶聚集诱导发光信息防伪软体机器人药物传递

Keywords

stimuli-responsive hydrogelsaggregation-induced emissioninformation anti-counterfeitingsoft robotsdrug delivery

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Related Institution

College of Chemistry and Chemical Engineering， Inner Mongolia Key Laboratory of Fine Organic Synthesis， Inner Mongolia University

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