GdF3∶Nd3+,Yb3+@NaGdF4 Nanomaterials for Near Infrared Fluorescence and Magnetic Resonance Dual-mode Imaging

Xu HE; Ya-nan WU; Yue-ning JIANG; Jing-tao LIU; Xian-xing XIANG; Cheng-xu WEN; Xu LI; Feng-he WANG

doi:10.37188/CJL.20210391

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GdF₃∶Nd³⁺,Yb³⁺@NaGdF₄ Nanomaterials for Near Infrared Fluorescence and Magnetic Resonance Dual-mode Imaging

Synthesis and Properties of Materials | 更新时间：2022-04-07

- GdF₃∶Nd³⁺,Yb³⁺@NaGdF₄ Nanomaterials for Near Infrared Fluorescence and Magnetic Resonance Dual-mode Imaging
  增强出版
- Chinese Journal of Luminescence Vol. 43, Issue 3, Pages: 350-358(2022)
- 作者机构：
  
  河北大学　物理科学与技术学院，河北　保定　071002
- 作者简介：
- 基金信息：
  
  Natural Science Foundation of Hebei Province(F2019201316);National Natural Science Foundation of China(51802069);The Central Project Guide local science and technology for development(216Z104G);Advanced Talents Incubation Program of the Hebei University(521000981236);Post-graduate's Innovation Fund Project of Hebei University(HUB2021ss066)
- DOI：10.37188/CJL.20210391
  CLC： O482.31
- Published：2022-03，
  
  Received：13 December 2021，
  
  Revised：29 December 2021，
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Xu HE, Ya-nan WU, Yue-ning JIANG, et al. GdF₃∶Nd³⁺,Yb³⁺@NaGdF₄ Nanomaterials for Near Infrared Fluorescence and Magnetic Resonance Dual-mode Imaging. [J]. Chinese Journal of Luminescence 43(3):350-358(2022)
DOI：

Xu HE, Ya-nan WU, Yue-ning JIANG, et al. GdF₃∶Nd³⁺,Yb³⁺@NaGdF₄ Nanomaterials for Near Infrared Fluorescence and Magnetic Resonance Dual-mode Imaging. [J]. Chinese Journal of Luminescence 43(3):350-358(2022) DOI： 10.37188/CJL.20210391.

摘要

利用Nd

与Yb

之间的能量传递，设计了808 nm激发下具有近红外光致发光的GdF

∶Nd

@NaGdF

磁性纳米探针。通过合成参数调控，研究了反应时间和前驱物浓度对GdF

∶Nd

材料形貌的影响。GdF

∶Nd

在808 nm激发下在近红外(NIR)第一/第二窗口具有较宽的发射峰(970~1 070 nm)，共掺杂体系实现了Yb

和Nd

双发光中心发光，有效提高了近红外区间的发光性能，同时克服了用980 nm激发的荧光成像引起生物组织过热的缺点。表面包覆NaGdF

惰性壳可以进一步提高GdF

∶Nd

的近红外发光强度，研究了不同厚度NaGdF

惰性壳对GdF

∶Nd

发光增强的影响。由于Gd

具有的顺磁特性，GdF

∶Nd

@NaGdF

显示出顺磁性能，磁化值为0.45 A·m

/kg，适合作为磁共振成像(MRI)T1探针。GdF

∶Nd

@NaGdF

纳米颗粒在NIR荧光成像和MRI领域具有广阔的应用前景。

Abstract

GdF

∶Nd

magnetic nanocomposites with near-infrared photoluminescence under 808 nm excitation were designed based on the energy transfer between Nd

and Yb

. The influence of synthesis parameters on the morphology of GdF

∶Nd

was discussed. The obtained GdF

∶Nd

exhibits a wide emission band(970-1 070 nm) under 808 nm excitation. The co-doping system of Nd

and Yb

can realize the dual emission center of Yb

and Nd

as the emission center. It effectively improves the luminescence performance in the near-infrared region and overcomes the disadvantage of overheating biological tissues by fluorescence imaging under 980 nm excitation. An inert shell of NaGdF

was grown on GdF

∶Nd

surface

which could improve the emission intensity dramatically. Meanwhile

the effect of NaGdF

inter shell with different thicknesses on the luminescence enhancement of GdF

∶Nd

was studied. The final products GdF

∶Nd

@NaGdF

are paramagnetic with magnetization 0.45 A·m

/kg. This indicates that GdF

∶Nd

@NaGdF

has broad application prospects in both the fluorescence imaging field and magnetic resonance imaging(MRI) field.

关键词

近红外能量传递磁共振成像

Keywords

near-infraredenergy transfermagnetic resonance imaging

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