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河北大学 物理科学与技术学院,河北 保定 071002
Published:2022-03,
Received:13 December 2021,
Revised:29 December 2021,
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XU HE, YA-NAN WU, YUE-NING JIANG, et al. GdF3∶Nd3+,Yb3+@NaGdF4 Nanomaterials for Near Infrared Fluorescence and Magnetic Resonance Dual-mode Imaging. [J]. Chinese journal of luminescence, 2022, 43(3): 350-358.
XU HE, YA-NAN WU, YUE-NING JIANG, et al. GdF3∶Nd3+,Yb3+@NaGdF4 Nanomaterials for Near Infrared Fluorescence and Magnetic Resonance Dual-mode Imaging. [J]. Chinese journal of luminescence, 2022, 43(3): 350-358. DOI: 10.37188/CJL.20210391.
利用Nd
3+
与Yb
3+
之间的能量传递,设计了808 nm激发下具有近红外光致发光的GdF
3
∶Nd
3+
Yb
3+
@NaGdF
4
磁性纳米探针。通过合成参数调控,研究了反应时间和前驱物浓度对GdF
3
∶Nd
3+
Yb
3+
材料形貌的影响。GdF
3
∶Nd
3+
Yb
3+
在808 nm激发下在近红外(NIR)第一/第二窗口具有较宽的发射峰(970~1 070 nm),共掺杂体系实现了Yb
3+
和Nd
3+
双发光中心发光,有效提高了近红外区间的发光性能,同时克服了用980 nm激发的荧光成像引起生物组织过热的缺点。表面包覆NaGdF
4
惰性壳可以进一步提高GdF
3
∶Nd
3+
Yb
3+
的近红外发光强度,研究了不同厚度NaGdF
4
惰性壳对GdF
3
∶Nd
3+
Yb
3+
发光增强的影响。由于Gd
3+
具有的顺磁特性,GdF
3
∶Nd
3+
Yb
3+
@NaGdF
4
显示出顺磁性能,磁化值为0.45 A·m
2
/kg,适合作为磁共振成像(MRI)T1探针。GdF
3
∶Nd
3+
Yb
3+
@NaGdF
4
纳米颗粒在NIR荧光成像和MRI领域具有广阔的应用前景。
GdF
3
∶Nd
3+
Yb
3+
magnetic nanocomposites with near-infrared photoluminescence under 808 nm excitation were designed based on the energy transfer between Nd
3+
and Yb
3+
. The influence of synthesis parameters on the morphology of GdF
3
∶Nd
3+
Yb
3+
was discussed. The obtained GdF
3
∶Nd
3+
Yb
3+
exhibits a wide emission band(970-1 070 nm) under 808 nm excitation. The co-doping system of Nd
3+
and Yb
3+
can realize the dual emission center of Yb
3+
and Nd
3+
as the emission center. It effectively improves the luminescence performance in the near-infrared region and overcomes the disadvantage of overheating biological tissues by fluorescence imaging under 980 nm excitation. An inert shell of NaGdF
4
was grown on GdF
3
∶Nd
3+
Yb
3+
surface
which could improve the emission intensity dramatically. Meanwhile
the effect of NaGdF
4
inter shell with different thicknesses on the luminescence enhancement of GdF
3
∶Nd
3+
Yb
3+
was studied. The final products GdF
3
∶Nd
3+
Yb
3+
@NaGdF
4
are paramagnetic with magnetization 0.45 A·m
2
/kg. This indicates that GdF
3
∶Nd
3+
Yb
3+
@NaGdF
4
has broad application prospects in both the fluorescence imaging field and magnetic resonance imaging(MRI) field.
近红外能量传递磁共振成像
near-infraredenergy transfermagnetic resonance imaging
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