Research Progresses on Chemiluminescent Gold Nanoclusters Applied in Biological <italic style="font-style: italic">in vitro</italic> Detection

Tian-hao XIA; Yun-peng WANG; Xiao-ru DAI; Shi-sheng LING; Dong CHEN; Xu-sheng QIAO; Xian-ping FAN

doi:10.37188/CJL.20210385

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Research Progresses on Chemiluminescent Gold Nanoclusters Applied in Biological in vitro Detection

Invited Review | 更新时间：2022-04-07

- Research Progresses on Chemiluminescent Gold Nanoclusters Applied in Biological in vitro Detection
  增强出版
- Chinese Journal of Luminescence Vol. 43, Issue 3, Pages: 314-326(2022)
- 作者机构：
  
  1.浙江大学材料科学与工程学院　硅材料国家重点实验室，浙江　杭州　310027
  2.杭州安旭生物科技有限公司，浙江　杭州　310011
- 作者简介：
- 基金信息：
  
  “Lingyan” research and development project of Zhejiang Province(2022C01142)
- DOI：10.37188/CJL.20210385
  CLC： O482.31
- Published：2022-03，
  
  Received：09 December 2021，
  
  Revised：27 December 2021，
- 稿件说明：
移动端阅览
TIAN-HAO XIA, YUN-PENG WANG, XIAO-RU DAI, et al. Research Progresses on Chemiluminescent Gold Nanoclusters Applied in Biological in vitro Detection. [J]. Chinese journal of luminescence, 2022, 43(3): 314-326.
DOI：

TIAN-HAO XIA, YUN-PENG WANG, XIAO-RU DAI, et al. Research Progresses on Chemiluminescent Gold Nanoclusters Applied in Biological in vitro Detection. [J]. Chinese journal of luminescence, 2022, 43(3): 314-326. DOI： 10.37188/CJL.20210385.

摘要

金纳米簇是一种制备工艺简单、具有分子级尺寸和量子效应的新型发光材料，近年来在化学发光检测中得到了广泛应用，特别是较多应用于体外生物检测。本文综述了金纳米簇化学发光(含电化学发光)体系在体外生物检测中的应用进展。首先，阐释了金纳米簇的合成方法、结构、性质及其化学发光基本原理；其次，总结了国内外近年来基于该体系的体外生物检测研究进展，并梳理了改善发光强度和检测灵敏度的已有策略；最后，对金纳米簇化学发光的未来发展趋势进行了展望。

Abstract

Gold nanoclusters are novel luminescent materials with simple preparation method

molecular size and quantum effect

which have been widely applied in chemiluminescence detection in recent years

especially in

in vitro

biological detection. This article reviews the progress of gold nanoclusters chemiluminescence(including electrochemiluminescence) system in the application of

in vitro

biological detection. First

the synthesis

structure

properties of gold nanoclusters and the basic principle of chemiluminescence system are introduced and explained theoretically. Next

recent reports are summarized on

in vitro

biological detection with gold nanoclusters

and strategies in literatures are overviewed and commented on how to improve the luminescent intensity and detection sensitivity. Finally

we give an outlook on the development trend of gold nanoclusters chemiluminescence system.

关键词

金纳米簇化学发光电化学发光体外生物检测

Keywords

gold nanoclusterschemiluminescenceelectrochemiluminescencein vitro biological detection

references

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Related Author

Tian-hao XIA

Yun-peng WANG

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Xu-sheng QIAO

Xian-ping FAN

Cheng-long SHEN

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Related Institution

State Key Laboratory of Silicon Materials & School of Materials Science and Engineering， Zhejiang University

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Research Progresses on Chemiluminescent Gold Nanoclusters Applied in Biological in vitro Detection

DOI：10.37188/CJL.20210385

摘要

Abstract

关键词

Keywords

references