Fabrication and Application of Fluorescence Biosensors Based on Carbon Dots and Aptamer

Zhi-cheng ZHU; Bai YANG

doi:10.37188/CJL.20210161

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Fabrication and Application of Fluorescence Biosensors Based on Carbon Dots and Aptamer

Invited Paper | 更新时间：2021-09-03

- Fabrication and Application of Fluorescence Biosensors Based on Carbon Dots and Aptamer
  增强出版
- Chinese Journal of Luminescence Vol. 42, Issue 8, Pages: 1196-1214(2021)
- 作者机构：
  
  1.吉林大学化学学院　超分子结构与材料国家重点实验室，吉林　长春　 130012
- 作者简介：
- 基金信息：
  
  National Natural Science Foundation of China(22035001)
- DOI：10.37188/CJL.20210161
  CLC：
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Zhi-cheng ZHU, Bai YANG. Fabrication and Application of Fluorescence Biosensors Based on Carbon Dots and Aptamer. [J]. Chinese Journal of Luminescence 42(8):1196-1214(2021)
DOI：

Zhi-cheng ZHU, Bai YANG. Fabrication and Application of Fluorescence Biosensors Based on Carbon Dots and Aptamer. [J]. Chinese Journal of Luminescence 42(8):1196-1214(2021) DOI： 10.37188/CJL.20210161.

摘要

近年来，基于碳点与适配体构建的荧光生物传感器引起了人们强烈的兴趣。与传统荧光染料、半导体量子点及稀土荧光材料相比，以碳点为荧光基元的生物传感器荧光稳定性更好，毒性更低，价格更便宜，在环境监测、生物成像及生物医疗方面有着广泛的应用前景。本文对基于碳点与适配体构建的荧光生物传感器发展现状进行了系统的总结，包括碳点与适配体介绍，近年来基于碳点与适配体的荧光生物传感器的构建方式、传感机理以及应用范围，最后对基于碳点与适配体构建的荧光生物传感器的发展方向进行了展望。

Abstract

Recently, the fluorescence biosensor based on carbon dots(CDs) and aptamer is more and more attractive. Comparing with traditional fluorescence materials like fluorescence dye, semiconductor quantum dots and rare earth phosphors, CDs have attracted considerable attention in the field of fluorescence biosensor due to their excellent photoluminescence, low toxicity and low-cost prepare process. The fluorescence biosensor based on CDs and aptamer has extensive application prospect in the field of environment monitoring, bioimaging and biomedicine. This review will summarize the structural composition, fabrication methods, sensing mechanism and application area of fluorescence biosensor based on CDs and aptamer.

关键词

碳点适配体荧光生物传感器传感机理

Keywords

carbon dotsaptamerfluorescence biosensorsensing mechanism

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