Research Progress on Design Strategy and Application of Persistent Luminescence Nanotheranostics

Ru KANG; Shao-an ZHANG; Hui-wang LIAN; Xing-zhong CHEN; Yang LI

doi:10.37188/CJL.20200275

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Research Progress on Design Strategy and Application of Persistent Luminescence Nanotheranostics

Invited Paper | 更新时间：2020-12-10

- Research Progress on Design Strategy and Application of Persistent Luminescence Nanotheranostics
- Chinese Journal of Luminescence Vol. 41, Issue 12, Pages: 1614-1626(2020)
- 作者机构：
  
  1.广东工业大学物理与光电工程学院, 广东广州 510006
  2.广州医科大学生物医学工程系, 广东广州 511436
  3.广东技术师范大学光电工程学院, 广东广州 510665
- 作者简介：
- 基金信息：
  
  National Natural Science Foundation of China;Natural Science Foundation of Guangdong Province;Science and Technology Program of Guangzhou
- DOI：10.37188/CJL.20200275
  CLC： O482.31
- Published：2020-12，
  
  Received：11 September 2020，
  
  Accepted：29 October 2020
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Ru KANG, Shao-an ZHANG, Hui-wang LIAN, et al. Research Progress on Design Strategy and Application of Persistent Luminescence Nanotheranostics. [J]. Chinese Journal of Luminescence 41(12):1614-1626(2020)
DOI：

Ru KANG, Shao-an ZHANG, Hui-wang LIAN, et al. Research Progress on Design Strategy and Application of Persistent Luminescence Nanotheranostics. [J]. Chinese Journal of Luminescence 41(12):1614-1626(2020) DOI： 10.37188/CJL.20200275.

摘要

长余辉纳米材料具有激发/发射分离、成像分辨率高、大面积成像与操作模式便捷等优点，在高灵敏度生物医学光学诊断领域引起了广泛关注。然而，随着诊疗一体化需求的增加，现有长余辉纳米材料功能的单一性阻碍了其在微型化、集成化诊疗上的快速发展。基于此，本综述针对生物医学诊疗集成一体化的长余辉纳米诊疗剂开发，展示了相应的设计策略和合成方法，并指出了长余辉纳米诊疗剂的研究前景、机遇及未来的发展方向。

Abstract

In virtue of the separation of excitation and emission

background-free autofluorescence

large area imaging and convenient operation

persistent luminescence nanoparticles(PLNPs) have attracted widespread attention in the field of optical diagnosis. However

with the increasing demand for integrated diagnosis and treatment

the single function of the existing PLNPs limits their technological breakthroughs in the miniaturized and integrated diagnosis and treatment units. Herein

in this review

PLNPs which can meet the integration requirements of biomedical diagnosis and treatment are discussed. Then the design strategies of developing these nanotheranostics are elaborated. Finally

the research opportunities for PLNPs nanotheranostics are prospected.

关键词

长余辉纳米诊疗剂生物成像药物治疗

Keywords

persistent luminescencenanotheranosticsbioimagingtreatment

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Related Institution

School of Physics and Optoelectronic Engineering， Guangdong University of Technology

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State Key Laboratory of Organic Electronics and Information Displays & Institute of Advanced Materials （IAM）， Nanjing University of Posts & Telecommunications

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine， Xiamen University

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