Research Progress on Design Strategy and Application of Persistent Luminescence Nanotheranostics

Ru KANG; Shao-an ZHANG; Hui-wang LIAN; Xing-zhong CHEN; Yang LI

doi:10.37188/CJL.20200275

您当前的位置：

首页 >

文章列表页 >

Research Progress on Design Strategy and Application of Persistent Luminescence Nanotheranostics

Invited Paper | 更新时间：2020-12-10

- Research Progress on Design Strategy and Application of Persistent Luminescence Nanotheranostics
- Chinese Journal of Luminescence Vol. 41, Issue 12, Pages: 1614-1626(2020)
- 作者机构：
  
  1.广东工业大学物理与光电工程学院, 广东广州 510006
  2.广州医科大学生物医学工程系, 广东广州 511436
  3.广东技术师范大学光电工程学院, 广东广州 510665
- 作者简介：
- 基金信息：
  
  National Natural Science Foundation of China;Natural Science Foundation of Guangdong Province;Science and Technology Program of Guangzhou
- DOI：10.37188/CJL.20200275
  CLC： O482.31
- Published：2020-12，
  
  Received：11 September 2020，
  
  Accepted：2020-10-29
- 稿件说明：
移动端阅览
RU KANG, SHAO-AN ZHANG, HUI-WANG LIAN, et al. Research Progress on Design Strategy and Application of Persistent Luminescence Nanotheranostics. [J]. Chinese journal of luminescence, 2020, 41(12): 1614-1626.
DOI：

RU KANG, SHAO-AN ZHANG, HUI-WANG LIAN, et al. Research Progress on Design Strategy and Application of Persistent Luminescence Nanotheranostics. [J]. Chinese journal of luminescence, 2020, 41(12): 1614-1626. DOI： 10.37188/CJL.20200275.

摘要

长余辉纳米材料具有激发/发射分离、成像分辨率高、大面积成像与操作模式便捷等优点，在高灵敏度生物医学光学诊断领域引起了广泛关注。然而，随着诊疗一体化需求的增加，现有长余辉纳米材料功能的单一性阻碍了其在微型化、集成化诊疗上的快速发展。基于此，本综述针对生物医学诊疗集成一体化的长余辉纳米诊疗剂开发，展示了相应的设计策略和合成方法，并指出了长余辉纳米诊疗剂的研究前景、机遇及未来的发展方向。

Abstract

In virtue of the separation of excitation and emission

background-free autofluorescence

large area imaging and convenient operation

persistent luminescence nanoparticles(PLNPs) have attracted widespread attention in the field of optical diagnosis. However

with the increasing demand for integrated diagnosis and treatment

the single function of the existing PLNPs limits their technological breakthroughs in the miniaturized and integrated diagnosis and treatment units. Herein

in this review

PLNPs which can meet the integration requirements of biomedical diagnosis and treatment are discussed. Then the design strategies of developing these nanotheranostics are elaborated. Finally

the research opportunities for PLNPs nanotheranostics are prospected.

关键词

长余辉纳米诊疗剂生物成像药物治疗

Keywords

persistent luminescencenanotheranosticsbioimagingtreatment

references

PAN Z, LU Y, LIU F J N M. Sunlight-activated long-persistent luminescence in the near-infrared from Cr3+-doped zinc gallogermanates[J].Nat. Mater., 2012, 11(1):58-63.

LI Y, GECEVICIUS M, QIU J. Long persistent phosphors—from fundamentals to applications[J].Chem. Soc. Rev., 2016, 45(8):2090-2136.

WANG J, MA Q, WANG Y, et al.. Recent progress in biomedical applications of persistent luminescence nanoparticles[J].Nanoscale, 2017, 9(19):6204-6218.

马青兰, 黄远明.绿色长余辉铝酸盐在信息显示领域的应用探索[J].液晶与显示, 2010, 25(03):325-328.

MA Q L, HUANG Y M. Application of green aluminates phosphors in information display field[J].Chin. J. Liq. Cryst. Disp., 2010, 25(3):325-328. (in Chinese)

CHI F F, WEI X T, JIANG B, et al.. Luminescence properties and the thermal quenching mechanism of Mn2+ doped Zn2GeO4 long persistent phosphors[J].Dalton Trans., 2018, 47(4):1303-1311.

DE CLERCQ O Q, POELMAN D. Local, temperature-dependent trapping and detrapping in the LiGa5O8:Cr infrared emitting persistent phosphor[J].ECS J. Solid State Sci. Technol., 2018, 7(1):R3171-R3175.

LYU T S, DORENBOS P. Charge carrier trapping processes in lanthanide doped LaPO4, GdPO4, YPO4, and LuPO4[J].J. Mater. Chem. C, 2018, 6(2):369-379.

ABDUKAYUM A, CHEN J T, ZHAO Q, et al.. Functional near infrared-emitting Cr3+/Pr3+ co-doped zinc gallogermanate persistent luminescent nanoparticles with superlong afterglow for in vivo targeted bioimaging[J].J. Am. Chem. Soc., 2013, 135(38):14125-14133.

NIE J M, LI Y, HAN G, et al.. In vivo clearable inorganic nanophotonic materials:designs, materials and applications[J].Nanoscale, 2019, 11(27):12742-12754.

SUN S K, WANG H F, YAN X P. Engineering persistent luminescence nanoparticles for biological applications:from biosensing/bioimaging to theranostics[J].Acc. Chem. Res., 2018, 51(5):1131-1143.

CHEN L J, SUN S K, WANG Y, et al.. Activatable multifunctional persistent luminescence nanoparticle/copper sulfide nanoprobe for in vivo luminescence imaging-guided photothermal therapy[J].ACS Appl. Mater. Interfaces, 2016, 8(48):32667-32674.

MALDINEY T, BESSIÈRE A, SEGUIN J, et al.. The in vivo activation of persistent nanophosphors for optical imaging of vascularization, tumours and grafted cells[J].Nat. Mater., 2014, 13(4):418-426.

SHI J P, SUN X, ZHU J F, et al.. One-step synthesis of amino-functionalized ultrasmall near infrared-emitting persistent luminescent nanoparticles for in vitro and in vivo bioimaging[J].Nanoscale, 2016, 8(18):9798-9804.

LI Y J, YAN X P. Synthesis of functionalized triple-doped zinc gallogermanate nanoparticles with superlong near-infrared persistent luminescence for long-term orally administrated bioimaging[J].Nanoscale, 2016, 8(32):14965-14970.

KANG R, DOU X J, LIAN H W, et al.. SrAl12O19:Fe3+ @3-aminopropyl triethoxysilane:ambient aqueous stable near-infrared persistent luminescent nanocomposites[J].J. Am. Ceram. Soc., 2020, 103(1):258-265.

LI Y, CHEN R, LI Y, et al.. Folic acid-conjugated chromium(Ⅲ) doped nanoparticles consisting of mixed oxides of zinc, gallium and tin, and possessing near-infrared and long persistent phosphorescence for targeted imaging of cancer cells[J].Microchim. Acta, 2015, 182(9):1827-1834.

OZDEMIR T, LU Y C, KOLEMEN S, et al.. Generation of singlet oxygen by persistent luminescent nanoparticle-photosensitizer conjugates:a proof of principle for photodynamic therapy without light[J].ChemPhotoChem, 2017, 1(5):183-187.

WANG J, MA Q Q, HU X X, et al.. Autofluorescence-free targeted tumor imaging based on luminous nanoparticles with composition-dependent size and persistent luminescence[J].ACS Nano, 2017, 11(8):8010-8017.

WU S Q, YANG C X, YAN X P. A dual-functional persistently luminescent nanocomposite enables engineering of mesenchymal stem cells for homing and gene therapy of glioblastoma[J].Adv. Funct. Mater., 2017, 27(11):1604992-1-7.

XUE Z L, LI X L, LI Y B, et al.. X-ray-activated near-infrared persistent luminescent probe for deep-tissue and renewable in vivo bioimaging[J].ACS Appl. Mater. Interfaces, 2017, 9(27):22132-22142.

ZHAO H X, LIU C X, GU Z, et al.. Persistent luminescent nanoparticles containing hydrogels for targeted, sustained, and autofluorescence-free tumor metastasis imaging[J].Nano Lett., 2019, 20(1):252-260.

WONG X Y, SENA-TORRALBA A, ÁLVAREZ-DIDUK R, et al.. Nanomaterials for nanotheranostics:tuning their properties according to disease needs[J].ACS Nano, 2020, 14(3):2585-2627.

KANG R, NIE J M, DOU X J, et al.. Tunable NIR long persistent luminescence and discovery of trap-distribution-dependent excitation enhancement in transition metal doped weak-crystal-field CaZnGe2O6[J].J. Alloys Compd., 2018, 735:692-699.

LIANG L, CHEN N, JIA Y Y, et al.. Recent progress in engineering near-infrared persistent luminescence nanoprobes for time-resolved biosensing/bioimaging[J].Nano Res., 2019, 12(6):1279-1292.

WANG J, LI J L, YU J N, et al.. Large hollow cavity luminous nanoparticles with near-infrared persistent luminescence and tunable sizes for tumor afterglow imaging and chemo-/photodynamic therapies[J].ACS Nano, 2018, 12(5):4246-4258.

ZHANG J F, ZHANG J, LI W Y, et al.. Degradable hollow mesoporous silicon/carbon nanoparticles for photoacoustic imaging-guided highly effective chemo-thermal tumor therapy in vitro and in vivo [J].Theranostics, 2017, 7(12):3007-3020.

SHI J P, SUN M, SUN X, et al.. Near-infrared persistent luminescence hollow mesoporous nanospheres for drug delivery and in vivo renewable imaging[J].J. Mater. Chem. B, 2016, 4(48):7845-7851.

SHEN T T, ZHANG Y, KIRILLOV A M, et al.. Two-photon sensitized hollow Gd2O3:Eu3+ nanocomposites for real-time dual-mode imaging and monitoring of anticancer drug release[J].Chem. Commun., 2016, 52(7):1447-1450.

SLOWING I I, TREWYN B G, GIRI S, et al.. Mesoporous silica nanoparticles for drug delivery and biosensing applications[J].Adv. Funct. Mater., 2007, 17(8):1225-1236.

HUANG S S, CHENG Z Y, MA P A, et al.. Luminescent GdVO4:Eu3+ functionalized mesoporous silicananoparticles for magnetic resonance imaging and drug delivery[J].Dalton Trans., 2013, 42(18):6523-6530.

CHENG S H, LIAO W N, CHEN L M, et al.. pH-controllable release using functionalized mesoporous silicananoparticles as an oral drug delivery system[J].J. Mater. Chem., 2011, 21(20):7130-7137.

YUAN L, TANG Q Q, YANG D, et al.. Preparation of pH-responsive mesoporous silica nanoparticles and their application in controlled drug delivery[J].J. Phys. Chem. C, 2011, 115(20):9926-9932.

MANZANO M, VALLET-REGÍ M. Mesoporous silica nanoparticles for drug delivery[J].Adv. Funct. Mater., 2020, 30(2):1902634.

QIAO Z A, ZHANG L, GUO M Y, et al.. Synthesis of mesoporous silica nanoparticles via controlled hydrolysis and condensation of silicon alkoxide[J].Chem. Mater., 2009, 21(16):3823-3829.

SHI J P, SUN X, ZHENG S H, et al.. A new near-infrared persistent luminescence nanoparticle as a multifunctional nanoplatform for multimodal imaging and cancer therapy[J].Biomaterials, 2018, 152:15-23.

LI Z J, ZHANG Y W, WU X, et al.. In vivo repeatedly charging near-infrared-emitting mesoporous SiO2/ZnGa2O4:Cr3+ persistent luminescence nanocomposites[J].Adv. Sci., 2015, 2(3):1500001.

GUERRERO-MARTÍNEZ A, PÉREZ-JUSTE J, LIZ-MARZÁN L M. Recent progress on silica coating of nanoparticles and related nanomaterials[J].Adv. Mater., 2010, 22(11):1182-1195.

ZOU R, HUANG J J, SHI J P, et al.. Silica shell-assisted synthetic route for mono-disperse persistent nanophosphors with enhanced in vivo recharged near-infrared persistent luminescence[J].Nano Res., 2017, 10(6):2070-2082.

LI F F, WANG F Y, HU X, et al.. A long-persistent phosphorescent chemosensor for the detection of TNP based on CaTiO3:Pr3+@SiO2 photoluminescence materials[J].RSC Adv., 2018, 8(30):16603-16610.

DAI W B, LEI Y F, YE S, et al.. Mesoporous nanoparticles Gd2O3@mSiO2/ZnGa2O4:Cr3+, Bi3+ as multifunctional probes for bioimaging[J].J. Mater. Chem. B, 2016, 4(10):1842-1852.

LIN X H, SONG L, CHEN S, et al.. Kiwifruit-like persistent luminescent nanoparticles with high-performance and in situ activable near-infrared persistent luminescence for long-term in vivo bioimaging[J].ACS Appl. Mater. Interfaces, 2017, 9(47):41181-41187.

QIU X C, ZHU X J, XU M, et al.. Hybrid nanoclusters for near-infrared to near-infrared upconverted persistent luminescence bioimaging[J].ACS Appl. Mater. Interfaces, 2017, 9(38):32583-32590.

LU Z D, YIN Y D. Colloidal nanoparticle clusters:functional materials by design[J].Chem. Soc. Rev., 2012, 41(21):6874-6887.

CHEN O, RIEDEMANN L, ETOC F, et al.. Magneto-fluorescent core-shell supernanoparticles[J].Nat. Commun., 2014, 5:5093-1-16.

KIM J, LEE J E, LEE S H, et al.. Designed fabrication of a multifunctional polymer nanomedical platform for simultaneous cancer-targeted imaging and magnetically guided drug delivery[J].Adv. Mater., 2008, 20(3):478-483.

MENG H, LEONG W, LEONG K W, et al.. Walking the line:the fate of nanomaterials at biological barriers[J].Biomaterials, 2018, 174:41-53.

NABIL G, BHISE K, SAU S, et al.. Nano-engineered delivery systems for cancer imaging and therapy:recent advances, future direction and patent evaluation[J].Drug Discov. Today, 2019, 24(2):462-491.

SONG G S, HAO J L, LIANG C, et al.. Degradable molybdenum oxide nanosheets with rapid clearance and efficient tumor homing capabilities as a therapeutic nanoplatform[J].Angew. Chem. Int. Ed., 2016, 55(6):2122-2126.

LU G, LI S Z, GUO Z, et al.. Imparting functionality to a metal-organic framework material by controlled nanoparticle encapsulation[J].Nat. Chem., 2012, 4(4):310-316.

FÉREY G. Hybrid porous solids:past, present, future[J].Chem. Soc. Rev., 2008, 37(1):191-214.

HORIKE S, SHIMOMURA S, KITAGAWA S. Soft porous crystals[J].Nat. Chem., 2009, 1(9):695-704.

CHEN L, YE J W, WANG H P, et al.. Ultrafast water sensing and thermal imaging by a metal-organic framework with switchable luminescence[J].Nat. Commun., 2017, 8:15985-1-10.

MURRAY L J, DINCǍ M, LONG J R. Hydrogen storage in metal-organic frameworks[J].Chem. Soc. Rev., 2009, 38(5):1294-1314.

LI J R, KUPPLER R J, ZHOU H C. Selective gas adsorption and separation in metal-organic frameworks[J].Chem. Soc. Rev., 2009, 38(5):1477-1504.

LEE J, FARHA O K, ROBERTS J, et al.. Metal-organic framework materials as catalysts[J].Chem. Soc. Rev., 2009, 38(5):1450-1459.

ALLENDORF M D, BAUER C A, BHAKTA R K, et al.. Luminescent metal-organic frameworks[J].Chem. Soc. Rev., 2009, 38(5):1330-1352.

ZHAO H X, SHU G, ZHU J Y, et al.. Persistent luminescent metal-organic frameworks with long-lasting near infrared emission for tumor site activated imaging and drug delivery[J].Biomaterials, 2019, 217:119332.

ZHENG H Q, ZHANG Y N, LIU L F, et al.. One-pot synthesis of metal-organic frameworks with encapsulated target molecules and their applications for controlled drug delivery[J].J. Am. Chem. Soc., 2016, 138(3):962-968.

LV Y, DING D D, ZHUANG Y X, et al.. Chromium-doped zinc gallogermanate@zeolitic imidazolate framework-8:a multifunctional nanoplatform for rechargeable in vivo persistent luminescence imaging and pH-responsive drug release[J].ACS Appl. Mater. Interfaces, 2019, 11(2):1907-1916.

YANG Z, SONG J B, TANG W, et al.. Stimuli-responsive nanotheranostics for real-time monitoring drug release by photoacoustic imaging[J].Theranostics, 2019, 9(2):526-536.

ZHANG D, ZHENG A X, LI J, et al.. Smart Cu(Ⅱ)-aptamer complexes based gold nanoplatform for tumor micro-environment triggered programmable intracellular prodrug release, photodynamic treatment and aggregation induced photothermal therapy of hepatocellular carcinoma[J].Theranostics, 2017, 7(1):164-179.

MALDINEY T, DOAN B T, ALLOYEAU D, et al.. Gadolinium-doped persistent nanophosphors as versatile tool for multimodal in vivo imaging[J].Adv.Funct. Mater., 2015, 25(2):331-338.

WU S Q, LI Y, DING W H, et al.. Recent advances of persistent luminescence nanoparticles in bioapplications[J].Nano-Micro Lett., 2020, 12(1):70-1-26.

CHUANG Y J, ZHEN Z P, ZHANG F, et al.. Photostimulable near-infrared persistent luminescent nanoprobes for ultrasensitive and longitudinal deep-tissue bio-imaging[J].Theranostics, 2014, 4(11):1112-1122.

LIU H H, REN F, ZHOU X G, et al.. Ultra-sensitive detection and inhibition of the metastasis of breast cancer cells to adjacent lymph nodes and distant organs by using long-persistent luminescence nanoparticles[J].Anal. Chem., 2019, 91(23):15064-15072.

LU Y C, YANG C X, YAN X P. Radiopaque tantalum oxide coated persistent luminescent nanoparticles as multimodal probes for in vivo near-infrared luminescence and computed tomography bioimaging[J].Nanoscale, 2015, 7(42):17929-17937.

崔继承, 唐玉国, 撖芃芃, 等.用于肿瘤手术在线诊断的成像光谱仪的研制[J].光学精密工程, 2013, 21(12):3043-3049.

CUI J C, TANG Y G, HAN P P, et al.. Development of diagnostic imaging spectrometer for tumor on-line operation[J].Opt. Precis. Eng., 2013, 21(12):3043-3049. (in Chinese)

MALDINEY T, BALLET B, BESSODES M, et al.. Mesoporous persistent nanophosphors for in vivo optical bioimaging and drug-delivery[J].Nanoscale, 2014, 6(22):13970-13976.

LIU J H, LÉCUYER T, SEGUIN J, et al.. Imaging and therapeutic applications of persistent luminescence nanomaterials[J].Adv. Drug Deliv. Rev., 2019, 138:193-210.

CHEN L J, YANG C X, YAN X P. Liposome-coated persistent luminescence nanoparticles as luminescence trackable drug carrier for chemotherapy[J].Anal. Chem., 2017, 89(13):6936-6939.

FENG Y, LIU R, ZHANG L C, et al.. Raspberry-like mesoporous Zn1.07Ga2.34Si0.98O6.56:Cr0.01 nanocarriers for enhanced near-infrared afterglow imaging and combined cancer chemotherapy[J].ACS Appl. Mater. Interfaces, 2019, 11(48):44978-44988.

昝明辉, 饶浪, 谢伟, 等.细胞膜伪装的纳米载体用于光热治疗的研究进展[J].中国光学, 2018, 11(3):392-400.

ZAN M H, RAO L, XIE W, et al.. Advances in cell membrane-camouflaged nano-carrier for photothermal therapy[J].Chin. Opt., 2018, 11(3):392-400. (in Chinese)

郑爱仙, 张晓龙, 刘小龙.核酸功能化纳米探针在细胞荧光成像中的应用[J].中国光学, 2018, 11(3):363-376.

ZHENG A X, ZHANG X L, LIU X L. Application in nucleic acid functionalized nanoprobe in cellular fluorescence imaging[J].Chin. Opt., 2018, 11(3):363-376. (in Chinese)

Views

272

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Thermoluminescence Dynamics Analysis and Its Application in Study of Persistent Luminescence Materials

Advances of NIR-Ⅱ Small Organic Molecules in Bioimaging and Therapy Based on Benzothiadiazole Structure

Fluorescence Mechanism and Biomedical Applications of pH-responsive Carbon Dots

Preparation, Optical Control and Application of Red/Near Infrared Emitting Carbon Dots

Related Author

LI-yang

Ru KANG

Xing-zhong CHENG

Hui-wang LIAN

Shao-an ZHANG

LIU Quanlin

SONG Zhen

BAI Xin

Related Institution

School of Physics and Optoelectronic Engineering， Guangdong University of Technology

School of Basic Medical Sciences， Guangzhou Medical University

School of Optoelectronic Engineering， Guangdong Normal University of Technology

School of Materials Science & Engineering， University of Science and Technology Beijing

State Key Laboratory of Organic Electronics and Information Displays & Institute of Advanced Materials （IAM）， Nanjing University of Posts & Telecommunications

Address：No.3888 Dong Nanhu Road, Changchun, Jilin, China Postal code：130033
Tel：0431-86176862 Email：fgxbt@126.com
Technical support is provided by Beijing Founder electronics co., LTD 吉ICP备11002662号-17 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰