CdTe和CdTe/CdS量子点与叶酸分子荧光相互作用

李光旻; 刘淏洋; 杨洋; 刘洪飞; 费学宁; 刘伟

doi:10.37188/CJL.20210257

您当前的位置：

首页 >

文章列表页 >

CdTe和CdTe/CdS量子点与叶酸分子荧光相互作用

发光学应用及交叉前沿 | 更新时间：2021-12-17

- CdTe和CdTe/CdS量子点与叶酸分子荧光相互作用
  增强出版
- Fluorescence Interaction Between Folate Molecules and CdTe and CdTe/CdS Quantum Dots
- 发光学报 2021年42卷第12期页码：1944-1950
- 作者机构：
  
  1.天津城建大学　理学院，天津　300384
  2.中企众鑫(天津)工业设计有限公司，天津　300384
- 作者简介：
  
  [ "李光旻(1979-)，男，天津人，博士，副教授，2015年于南开大学获得博士学位，主要从事无机手性量子点及荧光探针的研究。E-mail: 504753199@qq.com" ]
  [ "刘淏洋(2000-)，男，四川攀枝花人，在读本科生，主要从事量子点荧光相互作用的研究。E-mail: tauceti@foxmail.com" ]
  [ "刘洪飞(1985-)，男，河北任丘人，博士，讲师，2013年于中国科学院半导体研究所获得博士学位，主要从事半导体材料掺杂改性方面的计算研究。E-mail: liuhongfei001@163.com" ]
- 基金信息：
  
  国家自然科学基金(51578360;51778398);天津市高等学校基本科研业务资助项目(170401017);天津市技术创新引导专项（基金）(21YDTPJC00970)
- DOI：10.37188/CJL.20210257
  中图分类号： O482.31
- 收稿：2021-08-08，
  
  修回：2021-09-01，
  
  纸质出版：2021-12
- 稿件说明：
移动端阅览
李光旻, 刘淏洋, 杨洋, 等. CdTe和CdTe/CdS量子点与叶酸分子荧光相互作用[J]. 发光学报, 2021,42(12):1944-1950.

Guang-min LI, Hao-yang LIU, Yang YANG, et al. Fluorescence Interaction Between Folate Molecules and CdTe and CdTe/CdS Quantum Dots[J]. Chinese Journal of Luminescence, 2021, 42(12): 1944-1950.
李光旻, 刘淏洋, 杨洋, 等. CdTe和CdTe/CdS量子点与叶酸分子荧光相互作用[J]. 发光学报, 2021,42(12):1944-1950. DOI： 10.37188/CJL.20210257.

Guang-min LI, Hao-yang LIU, Yang YANG, et al. Fluorescence Interaction Between Folate Molecules and CdTe and CdTe/CdS Quantum Dots[J]. Chinese Journal of Luminescence, 2021, 42(12): 1944-1950. DOI： 10.37188/CJL.20210257.

摘要

制备了水溶性半胱氨酸修饰的CdTe和CdTe/CdS核壳结构量子点，实现了对叶酸分子的特异性荧光标记，可作为具有应用潜力的叶酸浓度快速测定荧光探针。实验结果表明，叶酸分子可以使CdTe量子点发生明显的荧光猝灭，而在CdTe/CdS核壳结构量子点中，没有观察到这种猝灭行为。本文采用Stern-Volmer方程对荧光猝灭机制进行了分析，研究表明该猝灭机制是静态荧光猝灭。CdTe量子点在与叶酸分子作用过程中，荧光光谱发射峰发生了约35 nm的蓝移，热力学计算表明，量子点可能与叶酸分子通过静电作用形成了络合结构。

Abstract

Water soluble cysteine modified CdTe and CdTe/CdS core-shell quantum dots were prepared

which can realize the specific fluorescent labeling of folate molecules

and function as a fluorescent probe for detecting the concentration of folate. The experimental results showed that folate can cause obvious fluorescence quenching of CdTe quantum dots

but this quenching behavior was not observed in CdTe/CdS core-shell system. The fluorescence quenching mechanism was analyzed by Stern-Volmer equation

and the research showed that it was a static fluorescence quenching mechanism. The fluorescence emission spectrum had a blue shift of about 35 nm in the interaction between CdTe quantum dots and folate molecules. Thermodynamic calculation showed that a complex structure may be formed through electrostatic interaction between the quantum dots and folate molecules.

关键词

Keywords

references

SCHÖPS O , LE THOMAS N , WOGGON U , et al . Recombination dynamics of CdTe/CdS core-shell nanocrystals [J]. J. Phys. Chem. B , 2006 , 110 ( 5 ): 2074 - 2079 .

PURCELL-MILTON F , VISHERATINA A K , KUZNETSOVA V A , et al . Impact of shell thickness on photoluminescence and optical activity in chiral CdSe/CdS Core/Shell quantum dots [J]. ACS Nano , 2017 , 11 ( 9 ): 9207 - 9214 .

CHENG C Y , OU K L , HUANG W T , et al . Gadolinium-based CuInS2/ZnS nanoprobe for dual-modality magnetic resonance/optical imaging [J]. ACS Appl. Mater. Interfaces , 2013 , 5 ( 10 ): 4389 - 4400 .

ZHANG W J , CHEN G J , WANG J , et al . Design and synthesis of highly luminescent near-infrared-emitting water-soluble CdTe/CdSe/ZnS core/shell/shell quantum dots [J]. Inorg. Chem. , 2009 , 40 ( 20 ): 9723 - 9731 .

ALDEEK F , BALAN L , MEDJAHDI G , et al . Enhanced optical properties of core/shell/shell CdTe/CdS/ZnO quantum dots prepared in aqueous solution [J]. J. Phys. Chem. C , 2009 , 113 ( 45 ): 19458 - 19467 .

LI X W , CHEN L G . Fluorescence probe based on an amino-functionalized fluorescent magnetic nanocomposite for detection of folic acid in serum [J]. ACS Appl. Mater. Interfaces , 2016 , 8 ( 46 ): 31832 - 31840 .

CHAKRAVARTY S , DUTTA P , KALITA S , et al . PVA-based nanobiosensor for ultrasensitive detection of folic acid by fluorescence quenching [J]. Sens. Actuators B Chem. , 2016 , 232 : 243 - 250 .

JIANG H , WANG X M . Label-free detection of folate receptor (+) cells by molecular recognition mediated electrochemiluminescence of CdTe nanoparticles [J]. Anal. Chem. , 2014 , 86 ( 14 ): 6872 - 6878 .

VISHERATINA A K , ORLOVA A O , PURCELL-MILTON F , et al . Influence of CdSe and CdSe/CdS nanocrystals on the optical activity of chiral organic molecules [J]. J. Mater. Chem. C , 2018 , 6 ( 7 ): 1759 - 1766 .

SHANG L , BRANDHOLT S , STOCKMAR F , et al . Effect of protein adsorption on the fluorescence of ultrasmall gold nanoclusters [J]. Small , 2012 , 8 ( 5 ): 661 - 665 .

WANG H P , ZHENG C Z , DONG T J , et al . Wavelength dependence of fluorescence quenching of CdTe quantum dots by gold nanoclusters [J]. J. Phys. Chem. C , 2013 , 117 ( 6 ): 3011 - 3018 .

DE PAOLI LACERDA S H , PARK J J , MEUSE C , et al . Interaction of gold nanoparticles with common human blood proteins [J]. ACS Nano , 2010 , 4 ( 1 ): 365 - 379 .

GUILBAULT G G . Practical Fluorescence [M]. 2 nd ed. New York : Marcel Dekker Inc , 1990 .

JAGADEESWARI S , JHONSI M A , KATHIRAVAN A , et al . Photoinduced interaction between MPA capped CdTe QDs and certain anthraquinone dyes [J]. J. Lumin. , 2011 , 131 ( 4 ): 597 - 602 .

JHONSI M A , RENGANATHAN R . Investigations on the photoinduced interaction of water soluble thioglycolic acid (TGA) capped CdTe quantum dots with certain porphyrins [J]. J. Colloid Interface Sci. , 2010 , 344 ( 2 ): 596 - 602 .

GAPONIK N , TALAPIN D V , ROGACH A L , et al . Thiol-capping of CdTe nanocrystals:an alternative to organometallic synthetic routes [J]. J. Phys. Chem. B , 2002 , 106 ( 29 ): 7177 - 7185 .

PENG H , ZHANG L J , SOELLER C , et al . Preparation of water-soluble CdTe/CdS core/shell quantum dots with enhanced photostability [J]. J. Lumin. , 2007 , 127 ( 2 ): 721 - 726 .

董飞 , 刘江国 , 杨逸仙 , 等 . 一维CdTe纳米线与牛血清白蛋白的相互作用研究 [J]. 光散射学报 , 2010 , 22 ( 1 ): 65 - 71 .

DONG F , LIU J G , YANG Y X , et al . Study on the Interaction between CdTe nanowire and bovine serum album [J]. J. Light Scattering , 2010 , 22 ( 1 ): 65 - 71 . (in Chinese)

浏览量

726

下载量

CSCD

文章被引用时，请邮件提醒。

提交

工具集

关联资源

叶酸修饰的AgInS₂量子点在体外癌细胞成像上的应用

CdSe量子点“开关”的构建及其在药物分析中的应用

以巯基丙酸为稳定剂的水溶性CdTe量子点的水热合成及表征

近红外激发/发射的CuInSe₂量子点控制合成与三磷酸腺苷检测