Fiber optical biosensor is a significant kind of modern biosensor systems.At present

many fiber optical biosensor systems depending on detecting fluorescence have been on sale

but they almost obtain the bio-informatics by the intensity of fluorescence which comes from the fluorescent indicator.On the other side

the fiber optical biosensor systems that could get the bio-informatics directly from the self-fluorescence(spectrum) of biologic samples have not come into the market.In this situation

the author started some research on the samples of fresh human breast tissues by a self-made three-dimensional fluorescence fiber optical(spectrometer.) With the results

it's found that there are many obvious differences in the self-fluorescence(spectrum) between the normal and cancerous tissues.In details

the peak value in normal tissue is on the(position) of 511 nm

while it is on the position of 513 nm around the cancerous tissue

518 nm in the core of cancerous tissue.We can observe that the position of peak value has a trend to shift to red side from normal to(cancerous) tissues.On the other side

the intensity ratio of two primary peaks in normal tissue is 0.77

while it is 0.64(around) the cancerous tissue and 0.58 in the core of cancerous tissue.We can observe that there is a decreasing trend from normal to cancerous tissues.Furthermore

the source of the spectral difference and the origin of different fluorescent bands are analyzed.Although there are still much work to do and lots of elements to reveal

it is definitely obvious that the fluorescence spectrum technique combined with fiber optical sensors technique would make great progress in on-line diagnosis of human cancer in near future.