SL and SLIV to inhibit lipid peroxidation(LPO)in vitro and in vivo have been studied.In vitro
the concentration-dependent decreases of ultraweak chemiluninescence were observed when CHM
SL and SLIV were added to both Fe
2+
-lindenic Acid-BAS and Fe
2+
-Brain Homogenate system respectively.In vivo
CHM may contribute to the reinforcement and recovery of antiperoxidation abilities of γ-ray-treated mice by increasing the activity of SeGSH-Px.SL and SLIV can protect ischemic-reperfused Mongolian Gerbil against LPO injuries by enhancing the value of SeGSH-Px/MDA.CHM
SL and SLIV also can protect brain tissue against LPO in vivo
shown as lower level of brain homogenate natural or induced chemiluminescence.