Kang Jian, Xu Min, Chu Junjie, Teng Baiqin, Cui Xiuyun. REGULATORY EFFECTS OF PLATELETS ON CHEMILUMINESCENCE OF POLYMOR-PHONUCLEAR LEUKOCYTES[J]. Chinese Journal of Luminescence, 1993,14(4): 378-383
Kang Jian, Xu Min, Chu Junjie, Teng Baiqin, Cui Xiuyun. REGULATORY EFFECTS OF PLATELETS ON CHEMILUMINESCENCE OF POLYMOR-PHONUCLEAR LEUKOCYTES[J]. Chinese Journal of Luminescence, 1993,14(4): 378-383DOI:
Release of ATP/ADP from platelets causes enhanced oxygen radical species responses in polymorphonuclear leukocytes stimulated by FMLP or zymosan. The effect of platelets and adenosine nucleotides on production of oxygen radical species of polymorphonuclear leukocytes is concentration dependent. Platelets exert a priming effect on the generation of oxygen radical species at low platelet-to-PMN ratios but also have an inhibitory of effect on oxygen radical species production from PMN when higher platelet-to-PMN ratio are used. Identical biphasic effect were also observed when ATP or ADP was substituted for platelets.