Synthesis and Optical Properties of Ketone-formaldehyde Fluorescence Probe

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Synthesis and Optical Properties of Ketone-formaldehyde Fluorescence Probe

更新时间：2020-08-12

- Synthesis and Optical Properties of Ketone-formaldehyde Fluorescence Probe
- Chinese Journal of Luminescence Vol. 39, Issue 9, Pages: 1317-1322(2018)
- 作者机构：
  
  1. 山东省标准化研究院,山东济南,250014
  2. 齐鲁工业大学(山东省科学院) 山东省科学院新材料研究所, 山东省特种含硅新材料重点实验室, 山东济南 250014
  3. 山东省计量科学研究院, 山东济南 250014
- 作者简介：
- 基金信息：
  
  Supported by National Natural Science Foundation for Youth of China(51303097);Natu
- DOI：10.3788/fgxb20183909.1317
  CLC： O625.67
- Received：30 November 2017，
  
  Revised：25 March 2018，
  
  Published Online：10 April 2018，
  
  Published：05 September 2018
- 稿件说明：
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张硕, 李龙龙, 赵宁等. 酮类甲醛荧光探针的合成及其光学性质[J]. 发光学报, 2018,39(9): 1317-1322

ZHANG Shuo, LI Long-long, ZHAO Ning etc. Synthesis and Optical Properties of Ketone-formaldehyde Fluorescence Probe[J]. Chinese Journal of Luminescence, 2018,39(9): 1317-1322
张硕, 李龙龙, 赵宁等. 酮类甲醛荧光探针的合成及其光学性质[J]. 发光学报, 2018,39(9): 1317-1322 DOI： 10.3788/fgxb20183909.1317.

ZHANG Shuo, LI Long-long, ZHAO Ning etc. Synthesis and Optical Properties of Ketone-formaldehyde Fluorescence Probe[J]. Chinese Journal of Luminescence, 2018,39(9): 1317-1322 DOI： 10.3788/fgxb20183909.1317.

摘要

设计合成了两种化合物4-氨基4-（4-甲氧基苯基）-3-丁烯-2-酮（1b）和4-氨基-4-（1，3-亚甲二氧基苯基-5-基）-3-丁烯-2-酮（2b），测试了其在不同甲醛含量下的紫外吸收光谱及单光子荧光光谱。当含有100 mol/L和5 mol/L的甲醛时，化合物1b和2b的紫外吸收峰强度分别达到其最大值。在单光子荧光方面，化合物1b的荧光发射峰位置在384 nm，与紫外吸收峰相比红移50 nm。化合物2b的荧光发射峰呈现出双峰形状，其发射峰位置分别在384 nm及411 nm左右。当加入15 mol/L的甲醛时，化合物2b的411 nm处的荧光发射峰明显增强，两峰的重叠程度降低，可作为检测甲醛的特征变化。以上数据表明，化合物1b和2b不仅能够对微量甲醛产生响应，也可作为一种理想平台为更进一步拓宽化合物1b和2b在监测生物体系中甲醛荧光生物成像上的应用奠定理论基础。

Abstract

Two new vinylmethylketone derivative

4-amino-4-(4-methoxyphenyl) but-3-en-2-one (1b) and 4-amino-4-(1

3-benzodioxol-5-yl) but-3-en-2-one(2b) were synthesized and investigated as a possible fluorescent probe for formaldehyde detection. The linear absorption and fluorescent spectra of 1b and 2b in different formaldehyde concentration were investigated. The results indicate that the compound 1b and 2b have a intricate variation trend existing in UV-Vis absorption spectra and one-photon fluorescence spectra

respectively. In terms of single photon fluorescence

the fluorescence emission peak of compound 1b is located at 384 nm

which is 50 nm red shift compared with UV absorption peak. The fluorescence emission peak of compound 2b consists of two peaks located at 384 nm and 411 nm

respectively. When 15 mol/L of formaldehyde is added

the fluorescence emission peak of the compound 2b is obviously enhanced and the overlap degree of the two peak is reduced

which can be used to detect the characteristics of formaldehyde. These results show that 4-amino-4-(4-methoxyphenyl) but-3-en-2-one(1b) and 4-amino-4-(1

3-benzodioxol-5-yl) but-3-en-2-one(2b) are able to be as a promising candidate for formaldehyde detection.

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references

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