WU Hong-mei, GUO Yu, CAO Jian-fang etc. Synthesis and Spectral Analysis of Metal-organic Macrocyclic Compound for Detection of Glucosamine[J]. Chinese Journal of Luminescence, 2018,39(8): 1163-1169
WU Hong-mei, GUO Yu, CAO Jian-fang etc. Synthesis and Spectral Analysis of Metal-organic Macrocyclic Compound for Detection of Glucosamine[J]. Chinese Journal of Luminescence, 2018,39(8): 1163-1169 DOI: 10.3788/fgxb20183908.1163.
Synthesis and Spectral Analysis of Metal-organic Macrocyclic Compound for Detection of Glucosamine
Double-tridentate ligand LD was synthesized by 5-aminophthalic acid through esterification
hydrazinolysis and Schiff's base reactions. Then
a novel metal-organic macrocyclic LD-Zn was built by the assembly of LD and zinc ions for the recognition of glucosamine. The detection mechanism of glucosamine with LD-Zn was studied by UV-Vis
1
H NMR and ESI-MS. The results of
1
H NMR and ESI-MS indicate that the glucosamine molecules could enter the LD-Zn. Moreover
1:1 stoichiometric host-guest complexation between glucosamine and LD-Zn was formed. UV-Vis spectra show that the intensity of the absorption peak at 373 nm increased significantly after addition of glucosamine into LD-Zn. However
the absorption intensity at 269 nm and 303 nm decreases. The equilibrium constant
K
reaches 4.1910
3
L/mol
and the minimum detection limit is 5.010
-6
mol/L. For comparison
the detection tests of glucose and triethylamine with LD-Zn were carried out. The UV-Vis spectra do not show any response when glucose and triethylamine are added to LD-Zn. These results indicate that the structure of glucosamine is more compatible with the cavity of the macrocycle LD-Zn compared to glucose and triethylamine. The recognition of glucosamine by using LD-Zn is not attributed to pure hydroxyl(hydrogen bonding) or amino(alkaline)
it is mainly caused by the joint effect of confined cavity of LD-Zn molecular and hydrogen bonds of amino.
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