Optical Oxygen Nanosensors Towards Biomedical Applications

PENG Hong-shang; SHEN Rui-ying; WANG Xiao-hui

doi:10.3788/fgxb20163710.1167

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Optical Oxygen Nanosensors Towards Biomedical Applications

更新时间：2020-08-12

- Optical Oxygen Nanosensors Towards Biomedical Applications
- Chinese Journal of Luminescence Vol. 37, Issue 10, Pages: 1167-1176(2016)
- 作者机构：
  
  1. 北京交通大学理学院, 北京 100044
  2. 中央民族大学理学院, 北京 100081
- 作者简介：
- 基金信息：
- DOI：10.3788/fgxb20163710.1167
  CLC： O433.4;O482.31
- Received：07 August 2016，
  
  Revised：21 August 2016，
  
  Published：05 October 2016
- 稿件说明：
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彭洪尚, 申睿颖, 王小卉. 面向生物医学应用的光学氧气纳米传感器[J]. 发光学报, 2016,37(10): 1167-1176

PENG Hong-shang, SHEN Rui-ying, WANG Xiao-hui. Optical Oxygen Nanosensors Towards Biomedical Applications[J]. Chinese Journal of Luminescence, 2016,37(10): 1167-1176
彭洪尚, 申睿颖, 王小卉. 面向生物医学应用的光学氧气纳米传感器[J]. 发光学报, 2016,37(10): 1167-1176 DOI： 10.3788/fgxb20163710.1167.

PENG Hong-shang, SHEN Rui-ying, WANG Xiao-hui. Optical Oxygen Nanosensors Towards Biomedical Applications[J]. Chinese Journal of Luminescence, 2016,37(10): 1167-1176 DOI： 10.3788/fgxb20163710.1167.

摘要

在生物医学领域，溶氧的检测具有十分重要的意义。近年来氧气传感器的研究取得了重要的进展，尤其是纳米尺寸的光学氧气传感器倍受重视。光学氧气纳米传感器具有检测灵敏度高、稳定性好、易于生物功能化等优点，特别适用于在（亚）细胞层次或者生物组织内溶氧的实时检测。本文主要从氧气荧光探针的种类、传感器的基质构成、纳米传感器的构建方法、检测模式和生物医学应用等几个方面出发，结合本研究组在光学氧气纳米传感器的研究进展进行综述，并对其在生物医学领域中的主要应用进行了阐述。

Abstract

The determination of oxygen concentration is of great importance in biological applications. In recent years

significant progress has been made in the field

and nanosized optical oxygen sensors have gained particular attraction owing to the merit of high sensitivity

good photostability

facile bioconjugation and ideal dimension for

in vitro

and

in vivo

applications. In this review

we focus on optical oxygen nanosensors

including the types of suitable oxygen probes

structure properties

preparation methods

and different detection modalities. In addition

for different O

nanosensors

the analytical performance and applicability in specific biological applications are also outlined. Generally this review is meant to give the potential user a guide to select the most suitable optical oxygen nanosensor and detection modalities for their particular biological detection.

关键词

Keywords

references

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