Fluorescence Interaction Between Folate Molecules and CdTe and CdTe/CdS Quantum Dots

Guang-min LI; Hao-yang LIU; Yang YANG; Hong-fei LIU; Xue-ning FEI; Wei LIU

doi:10.37188/CJL.20210257

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Fluorescence Interaction Between Folate Molecules and CdTe and CdTe/CdS Quantum Dots

Luminescence Applications and Interdisciplinary Fields | 更新时间：2021-12-17

- Fluorescence Interaction Between Folate Molecules and CdTe and CdTe/CdS Quantum Dots
  增强出版
- Chinese Journal of Luminescence Vol. 42, Issue 12, Pages: 1944-1950(2021)
- 作者机构：
  
  1.天津城建大学　理学院，天津　300384
  2.中企众鑫(天津)工业设计有限公司，天津　300384
- 作者简介：
- 基金信息：
  
  National Natural Science Foundation of China(51578360;51778398);Tianjin municipal scientific research project(170401017);Tianjin Special Fund for Technological Innovation Guidance(21YDTPJC00970)
- DOI：10.37188/CJL.20210257
  CLC： O482.31
- Received：08 August 2021，
  
  Revised：2021-09-01，
  
  Published：2021-12
- 稿件说明：
移动端阅览
Guang-min LI, Hao-yang LIU, Yang YANG, et al. Fluorescence Interaction Between Folate Molecules and CdTe and CdTe/CdS Quantum Dots[J]. Chinese Journal of Luminescence, 2021, 42(12): 1944-1950.
DOI：

Guang-min LI, Hao-yang LIU, Yang YANG, et al. Fluorescence Interaction Between Folate Molecules and CdTe and CdTe/CdS Quantum Dots[J]. Chinese Journal of Luminescence, 2021, 42(12): 1944-1950. DOI： 10.37188/CJL.20210257.

摘要

制备了水溶性半胱氨酸修饰的CdTe和CdTe/CdS核壳结构量子点，实现了对叶酸分子的特异性荧光标记，可作为具有应用潜力的叶酸浓度快速测定荧光探针。实验结果表明，叶酸分子可以使CdTe量子点发生明显的荧光猝灭，而在CdTe/CdS核壳结构量子点中，没有观察到这种猝灭行为。本文采用Stern-Volmer方程对荧光猝灭机制进行了分析，研究表明该猝灭机制是静态荧光猝灭。CdTe量子点在与叶酸分子作用过程中，荧光光谱发射峰发生了约35 nm的蓝移，热力学计算表明，量子点可能与叶酸分子通过静电作用形成了络合结构。

Abstract

Water soluble cysteine modified CdTe and CdTe/CdS core-shell quantum dots were prepared

which can realize the specific fluorescent labeling of folate molecules

and function as a fluorescent probe for detecting the concentration of folate. The experimental results showed that folate can cause obvious fluorescence quenching of CdTe quantum dots

but this quenching behavior was not observed in CdTe/CdS core-shell system. The fluorescence quenching mechanism was analyzed by Stern-Volmer equation

and the research showed that it was a static fluorescence quenching mechanism. The fluorescence emission spectrum had a blue shift of about 35 nm in the interaction between CdTe quantum dots and folate molecules. Thermodynamic calculation showed that a complex structure may be formed through electrostatic interaction between the quantum dots and folate molecules.

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references

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