Interaction of Rare Earth with Bovine Serum Albumin

FENG Xiao-qiang; FU Guo-qing; LI Xiao-fang; YANG Sheng; SU Zhong-xing

doi:null

您当前的位置：

首页 >

文章列表页 >

Interaction of Rare Earth with Bovine Serum Albumin

paper | 更新时间：2020-08-12

- Interaction of Rare Earth with Bovine Serum Albumin
- Chinese Journal of Luminescence Vol. 32, Issue 2, Pages: 205-209(2011)
- 作者机构：
  
  1. 天水师范学院生命科学与化学学院,甘肃天水,741001
  2. 天水市中医医院,甘肃天水,741001
  3. 兰州大学化学化工学院,甘肃兰州,730030
- 作者简介：
- 基金信息：
- DOI：
  CLC： O657.3;O482.31
- Received：04 June 2010，
  
  Revised：2010-8-10，
  
  Published Online：22 February 2011，
  
  Published：22 February 2011
- 稿件说明：
移动端阅览
冯小强, 伏国庆, 李小芳, 杨声, 苏中兴. 稀土La(Ⅲ)、Nd(Ⅲ)与牛血清白蛋白的相互作用[J]. 发光学报, 2011,32(2): 205-209

FENG Xiao-qiang, FU Guo-qing, LI Xiao-fang, YANG Sheng, SU Zhong-xing. Interaction of Rare Earth with Bovine Serum Albumin[J]. Chinese Journal of Luminescence, 2011,32(2): 205-209
冯小强, 伏国庆, 李小芳, 杨声, 苏中兴. 稀土La(Ⅲ)、Nd(Ⅲ)与牛血清白蛋白的相互作用[J]. 发光学报, 2011,32(2): 205-209 DOI：

FENG Xiao-qiang, FU Guo-qing, LI Xiao-fang, YANG Sheng, SU Zhong-xing. Interaction of Rare Earth with Bovine Serum Albumin[J]. Chinese Journal of Luminescence, 2011,32(2): 205-209 DOI：

摘要

采用紫外吸收、荧光光谱和红外光谱

研究了稀土离子La(Ⅲ)和Nd(Ⅲ)与牛血清白蛋白(BSA)的相互作用。结果表明: La(Ⅲ)和Nd (Ⅲ)离子能配位诱导BSA

使其分子中色氨酸和酪氨酸芳杂环疏水基团外露

在280 nm处的吸收增强而表现出增色效应和较小的蓝移。La(Ⅲ)和Nd(Ⅲ)可以有规律地猝灭BSA的内源荧光

其猝灭机理是稀土离子与BSA形成复合物的静态猝灭。在20 ℃下

La(Ⅲ)和Nd (Ⅲ)与BSA的结合常数

分别为8.1210

和3.8510

。

Abstract

The interaction of rare earth La (Ⅲ) and Nd (Ⅲ) with BSA were studied by ultraviolet spectrum

fluorescence spectrum and IR spectrum. The results showed that the ultraviolet absorption intensity of BSA increases with the concentration of rare earth. Rare earth can strongly quench the fluorescence of BSA which is the static quenching. The binding constant (

) of La (Ⅲ) or Nd (Ⅲ) with BSA at room temperature are 8.1210

and 3.8510

respectively.

关键词

Keywords

references

Wang Dongmei, Liu Qingyun, Jian Jiangzhuang, et al. Synthesis and optical properties of transparent resins containing rare earth compounds [J]. Chin. J. Lumin. (发光学报), 2009, 30 (4):427-435 (in Chinese).[2] Cui Haixia, Chen Jianmin, Zhou Huidi. Synthesis and fluorescence properties of rare earth complex with a new diamidel ligand [J]. Chin. J. Lumin. (发光学报), 2009, 30 (4):457-462 (in Chinese).[3] Deng Ruwen, Zhang Zhongsheng. Rare earth medicine and pharmacy property [J]. Chin. Rare Earth (稀土), 1987,(3):36-47 (in Chinese).[4] Sugio S, Kashima A, Mochizuki S, et al. Crystal structure of human serum albumin at 2.5  resolution [J]. Protein Eng., 1999, 12 (6):439-446.[5] Liu Baosheng, Xue Chunli, Wang jing, et al. Studies on the interaction between ciprofloxacin and ofloxacin in presence of bovine serum albumin by spectroscopic methods [J]. Chin. J. Lumin. (发光学报), 2010, 31 (2):285-290.[6] Tang Bo, He Xiwen, Shen Hanxi. Analysis of synchronous and derivative synchronous fluorescence spectra of phenol and dihydroxybenzene [J]. Spectroscopy and Spectral Analysis (光谱学与光谱分析), 1998, 18 (1):21-26 (in Chinese).[7] Huang Bo, Zou Guolin, Yang Tianming. Studies on the interaction between adriamycin and bovine serum albumin [J]. Acta Chimica Sinica (化学学报), 2002, 60 (10):1867-1871 (in Chinese).[8] Xuan Guangshan, Wu Xiaonan, Li Yuping. Fluorescence study on the interaction of acetylsalicylic acid and bovine serum albumin [J]. Chin. J. Spectroscopy Laboratory (光谱实验室), 2005, 22 (7):861-864 (in Chinese).[9] Xie Mengxia, Xu Xiaoyun, Wang Yingdian. Spectroscopic investigation of the interaction between 2,3-dihydro- 4',5,7-trihydroxyflavone and human serum albumin [J]. Acta Chimica Sinica (化学学报), 2005, 63 (22):2055-2062 (in Chinese).[10] Chen Guozhen, HuangXianzhi, Zheng Zhuxing. Fluorescence Analytic Technique[M]. Beijing: Science Press, 1990:122.[11] Li Guizhi, Liu Yongming, Guo Xinyun, et al. Study on the interaction between bovine serum albumins and topotecan hydrochloride or irinotecan hydrochloride [J]. Acta Chimica Sinica (化学学报), 2006, 64 (7):679-685 (in Chinese).

Views

178

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Interaction Between Progesterone and Bovine Serum Albumin by Fluorescence Spectrum and Molecular Docking

Determination of Terazosin Hydrochloride by Using Bovine Serum Albumin as Fluorescent Probe

The Preliminary Analysis on the Fluorescence Spectra of Bilirubin in Human Serum

Research Progress in Photoluminescent Aerogels

Rare Earth Ion Doped Perovskite Nanocrystals

Related Author

YANG Shu-ling

LIAO Xian-ping

FAN Xing

TUO Xun

JI Ren-dong

ZHAO Zhi-min

ZHANG Ji-hua

CHEN Meng-lan

Related Institution

College of Chemistry, Nanchang University

School of Pharmacy, Nanchang University

College of Science, Nanjing University of Aeronautics and Astronautics

Faculty of Electronic and Electrical Engineering, Huaiyin Institute of Technology, Huaian

Chemistry Department, Northeast University

AI问答

Address：No.3888 Dong Nanhu Road, Changchun, Jilin, China Postal code：130033
Tel：0431-86176862 Email：fgxbt@126.com
Technical support is provided by Beijing Founder electronics co., LTD 吉ICP备11002662号-17 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰