Cu(Ⅰ) Ion Detection with Europium (Ⅲ) Chelate Nanoparticles Based on Click Chemistry

PENG Hong-shang; HUANG Shi-hua; LI Xiao-hua

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Cu(Ⅰ) Ion Detection with Europium (Ⅲ) Chelate Nanoparticles Based on Click Chemistry

paper | 更新时间：2020-08-12

- Cu(Ⅰ) Ion Detection with Europium (Ⅲ) Chelate Nanoparticles Based on Click Chemistry
- Chinese Journal of Luminescence Vol. 31, Issue 3, Pages: 411-415(2010)
- 作者机构：
  
  1. 北京交通大学光电子技术研究所教育部发光与光学信息重点实验室北京,100044
  2. 中国科学院化学所生命分析化学实验室北京,100190
- 作者简介：
- 基金信息：
- DOI：
  CLC： O657.3;O482.31
- Received：03 November 2009，
  
  Revised：02 January 1900，
  
  Published Online：30 June 2010，
  
  Published：30 June 2010
- 稿件说明：
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PENG Hong-shang, HUANG Shi-hua, LI Xiao-hua. Cu(Ⅰ) Ion Detection with Europium (Ⅲ) Chelate Nanoparticles Based on Click Chemistry[J]. Chinese journal of luminescence, 2010, 31(3): 411-415.
DOI：

PENG Hong-shang, HUANG Shi-hua, LI Xiao-hua. Cu(Ⅰ) Ion Detection with Europium (Ⅲ) Chelate Nanoparticles Based on Click Chemistry[J]. Chinese journal of luminescence, 2010, 31(3): 411-415. DOI：

摘要

制备了Eu (Ⅲ)配合物纳米颗粒并对其进行表面修饰以用于Cu(I)离子的检测。所采用的探测机制是源于Cu(I)离子催化的末端炔基和叠氮基团之间的1

3极性环加成。通过该反应

在Eu

配合物纳米颗粒(给体)和一种荧光染料分子(受体)之间建立了共振能量传递关系。因为点击反应的速度正比于Cu(I)离子的浓度

因此通过监测染料分子荧光强度的变化即可检测出Cu(I)离子的浓度。基于共振能量传递机制和点击反应的敏感性

浓度为微摩尔量级的Cu(I)离子可以被探测到。

Abstract

Europium (Ⅲ) chelate nanoparticles (NPs) were prepared and surface functionalized to detect Cu ( Ⅰ ) ions. The detection mechanism is based upon 1

3 dipolar cycloaddition of alkynyl groups to azido groups being able to be catalyzed by Cu( Ⅰ )

through which a fluorescent resonance energy transfer (FRET) system is constructed between NP and an acceptor fluorescent dye. By monitoring the fluorescence of the acceptor dye

the concentration of Cu ( Ⅰ ) ions was reported since the speed of click reaction is proportional to its concentration. Owing to the smart detecting scheme

Cu( Ⅰ ) ions (in micromolar concentrations) can be detected.

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references

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