Hydrolysis-activated Fluorophore System as a Molecular Sensor for Selective Detection of Zn2+

WU Hong-mei; HE Cheng; WANG Jian; ZHOU Peng

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Hydrolysis-activated Fluorophore System as a Molecular Sensor for Selective Detection of Zn²⁺

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- Hydrolysis-activated Fluorophore System as a Molecular Sensor for Selective Detection of Zn²⁺
- Chinese Journal of Luminescence Vol. 30, Issue 3, Pages: 275-284(2009)
- 作者机构：
  
  大连理工大学化学系精细化工国家重点实验室,辽宁大连,116012
- 作者简介：
- 基金信息：
- DOI：
  CLC： O482.31
- Received：25 November 2008，
  
  Revised：1900-1-2，
  
  Published Online：30 June 2009，
  
  Published：30 June 2009
- 稿件说明：
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吴红梅;何成;王健;周硼. 基于水解活性的Zn2+荧光探针[J]. 发光学报, 2009,30(3): 275-284

WU Hong-mei, HE Cheng, WANG Jian, ZHOU Peng. Hydrolysis-activated Fluorophore System as a Molecular Sensor for Selective Detection of Zn2+[J]. Chinese Journal of Luminescence, 2009,30(3): 275-284
吴红梅;何成;王健;周硼. 基于水解活性的Zn2+荧光探针[J]. 发光学报, 2009,30(3): 275-284 DOI：

WU Hong-mei, HE Cheng, WANG Jian, ZHOU Peng. Hydrolysis-activated Fluorophore System as a Molecular Sensor for Selective Detection of Zn2+[J]. Chinese Journal of Luminescence, 2009,30(3): 275-284 DOI：

摘要

合成了一种新颖的锌离子荧光探针N(2-羟基苄基)-4-(2-羟基苯亚甲基胺)-苯甲酰肼(HHB)

该探针本身的荧光较弱

但当它与Zn

配位时荧光增强

在475 nm处产生一较宽的发射光谱

量子产率

=0.59 (

=370 nm)。该化合物对Zn

具有良好的选择性能

环境生物体系中大量存在的碱金属和碱土金属离子K

和Ca

以及过渡金属离子Mn

和 Cu

等对Zn

的检测没有明显影响。在生命体系的pH值范围(6.8~7.7)

配合物HHB显示出对Zn

检测较高的灵敏度。作为比较文中还研究了HHB水解的主要产物4-氨基苄腙-水杨醛(HB)对Zn

的识别与传感性能。

Abstract

A new selective Zn

fluorescent sensor

N'-(2-hydroxybenzylidene)-4-(2-hydroxy-benzylidene-amino) benzohydrazide (HHB)

was synthesized. With the harbored 2-hydroxybenzylidene group

HHB exhibits an emission band centered at 475 nm with high quantum yield (

= 0.59) upon the addition of zinc ions. It features excellent fluorescence enhancement and provides favorable sensitivity for Zn

detection under the biological pH window of 6.8~7.7

and high selectivity for Zn

over biologically relevant alkali metals

alkaline earth metals and some of the first row transition metal. It works through the metal-assisted hydrolysis mechanism

and the hydrolysis residue sensor HB

salicylaldehyde-4-aminobenzoylhydrazone

was also investigated for comparison.

关键词

Keywords

references

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